ChemicalBook >> CAS DataBase List >>Catalpol
Catalpol
- CAS No.
- 2415-24-9
- Chemical Name:
- Catalpol
- Synonyms
- CATAPOL;CATALPOL;Catalpol-RM;catalpinoside;Catapol ,>=98%;Catalpol，Catalnol;CATALPOL WITH HPLC;Catalpol 2415-24-9;,6-beta,6a-alpha))-;Digitalis purpurea L
- CBNumber:
- CB6127844
- Molecular Formula:
- C15H22O10
- Molecular Weight:
- 362.33
- MDL Number:
- MFCD11111524
- MOL File:
- 2415-24-9.mol
Last updated:2025-01-27 09:38:02
| Melting point | 203-205°C |
|---|---|
| Boiling point | 675.6±55.0 °C(Predicted) |
| Density | 1.72±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) |
| form | Solid |
| pka | 12.79±0.70(Predicted) |
| color | White to Off-White |
| InChIKey | LHDWRKICQLTVDL-CLLMHHLUSA-N |
| LogP | -4.609 (est) |
| FDA UNII | JCX5L7JIC2 |
| UNSPSC Code | 41116107 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LZ5776816 | |||||||||
| HS Code | 29389090 | |||||||||
| Toxicity | mouse,LD,intravenous,> 2500mg/kg (2500mg/kg),Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 64, Pg. 93, 1968. | |||||||||
| NFPA 704 |
|
Catalpol price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89595 | Catalpol phyproof? Reference Substance | 2415-24-9 | 10MG | $521 | 2024-03-01 | Buy |
| Sigma-Aldrich | 50839 | Catalpol ≥96% (HPLC) | 2415-24-9 | 25mg | $306 | 2024-03-01 | Buy |
| Cayman Chemical | 24925 | Catalpol ≥98% | 2415-24-9 | 50mg | $60 | 2024-03-01 | Buy |
| Cayman Chemical | 24925 | Catalpol ≥98% | 2415-24-9 | 100mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 24925 | Catalpol ≥98% | 2415-24-9 | 250mg | $201 | 2024-03-01 | Buy |
Catalpol Chemical Properties,Uses,Production
Description
Catalpol is an iridoid glycoside that has been isolated from R. glutinosa and has diverse biological activities, including anti-apoptotic, pro-angiogenic, and radioprotective properties. It protects against mitochondrial pathway-dependent apoptosis in PC12 rat adrenal pheochromocytoma cells and H9c2 rat embryonic ventricular myocardial cells when used at a concentration of 10 μM. Catalpol pretreatment reduces apoptosis and improves viability in AHH-1 human lymphocyte cells exposed to ionizing radiation and reduces intestinal damage induced by radiation in mice when used at concentrations and doses ranging from of 25 to 100 μg/ml and 25 to 100 mg/kg, respectively. In a rat model of stroke, catalpol (5 mg/kg, i.p.) increases the expression of erythropoietin and VEGF and improves angiogenesis in the brain.
Chemical Properties
Light brown powder
Uses
Catapol is an iridoid glucoside that has been shown to alleviate neuropathic pain.
Definition
ChEBI: Catalpol is an organic molecular entity. It has a role as a metabolite.
Synthesis of Catalpol from [(1aS,1bα,5aα,6aβ)-2α-(β-D-Glucopyranosyloxy)-1a,1b,2,5a,6,6a-hexahydro-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-6α-yl]α-D-galactopyranoside
Catalpol Preparation Products And Raw materials
Global( 272)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20262 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29871 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 3772 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from Catalpol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-02-11 | Catalpol
2415-24-9
|
US $0.00-0.00 / g | 1g | 98 | 1000 | Wuhan Circle Star Chem-medical Technology Co.,Ltd | |
 |
2024-11-19 | Catalpol
2415-24-9
|
US $50.00 / mg | 99.84% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-04-23 | Catalpol
2415-24-9
|
US $1.00 / g | 1g | 99% | 10 tons | ANHUI WITOP BIOTECH CO., LTD |
2415-24-9(Catalpol)Related Search:
CATALPOL
,6-beta,6a-alpha))-
beta-d-glucopyranoside,1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)
catalpinoside
de(p-hydroxybenzoyl)catalposide
des-p-hydroxybenzoyl-catalposid
oxireno(4,5)cyclopenta(1,2-c)pyran-2-yl,(1as-(1a-alpha,1b-beta,2-beta,5a-beta
[1aS-(1aalpha,1bbeta,2beta,5abeta,6beta,6a.alpha.)]-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-beta-D-glucopyranoside
.beta.-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno4,5cyclopenta1,2-cpyran-2-yl
CATALPOL WITH HPLC
1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-
Catalpol，Catalnol
[(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside
Catapol ,>=98%
(1AS-(1aα,1bβ,2β,5aβ,6β,6aα-))1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxyMethyl)oxireno(4,5)cyclopenta(1,2-c)-pyran-2-yl-beta-D-glucopyranoside
(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside
Digitalis purpurea L
Catalpol 2415-24-9
Catalpol, ≥97%(HPLC)
(3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl
(2S,3R,4S,5S,6R)-2-[[(1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-2,5a,6,6a-tetrahydro-1bH-oxireno[5,6]cyclopenta[1,3-c]pyran-2-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
CATAPOL
(2S, 3R, 4S, 5S, 6R) -2- (((1aS, 1bS, 2S, 5aR, 6S, 6aS) -6-hydroxy-1a - (hydroxymethyl) -1a, 1b, 2,5a, 6,6a - hexahydroepoxyethano [2 ', 3': 4,5] cyclopentadieno [1,2-c] pyran-2-yl) oxy) -6- (hydroxymethyl) tetrahydro-2H-pyran-3,4,5-triol
(2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Catalpol-RM
Catalpol, 10 mM in DMSO
(2S,3R,4S,5S,6R)-2-[[(1S,2S,4S,5S,6R,10S)-5-hydroxy-2-(hydroxymethyl)-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-10-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
2415-24-9
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Inhibitors
Iridoids