FERULENOL
- CAS No.
- 6805-34-1
- Chemical Name:
- FERULENOL
- Synonyms
- FERULENOL;FERULENOL USP/EP/BP;Ferulenol, ATP synthesis inhibitor;4-Hydroxy-3-(3,7,11-trimethyl-2,6,10-dodecatrienyl)-coumarin;4-Hydroxy-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienyl]-2H-1-benzopyran-2-one;2H-1-Benzopyran-2-one, 4-hydroxy-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-
- CBNumber:
- CB4819349
- Molecular Formula:
- C24H30O3
- Molecular Weight:
- 366.49
- MDL Number:
- MFCD02183471
- MOL File:
- 6805-34-1.mol
- MSDS File:
- SDS
| Melting point | 55-56℃ |
|---|---|
| Boiling point | 525.3±50.0 °C(Predicted) |
| Density | 1.070±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| pka | 4.50±1.00(Predicted) |
| form | Off-white solid. |
| color | White to off-white |
| LogP | 7.730 (est) |
| FDA UNII | TG6L57MGV9 |
FERULENOL price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19568 | Ferulenol ≥95% | 6805-34-1 | 1mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 19568 | Ferulenol ≥95% | 6805-34-1 | 5mg | $157 | 2024-03-01 | Buy |
| Cayman Chemical | 19568 | Ferulenol ≥95% | 6805-34-1 | 10mg | $274 | 2024-03-01 | Buy |
| Usbiological | 044790 | Ferulenol | 6805-34-1 | 1mg | $282 | 2021-12-16 | Buy |
| TRC | F309003 | Ferulenol | 6805-34-1 | 1mg | $45 | 2021-12-16 | Buy |
FERULENOL Chemical Properties,Uses,Production
Uses
Ferulenol is antibiotic useful against mycobacteria similar to taxol.
Biological Activity
ferulenol is a prenylated 4-hydroxycoumarin derivative from ferula communis var. genuine with haemorrhagic action [1]. it has been demonstrated that ferulenol exihibits potent antimycobacterial activity [2].
in vitro
ferulenol stimulated tubulin polymerization in the absence of gtp, with a less extensive polymerization profile at 100 pm concentration. ferulenol decreased radiolabeled colchicine bound by tubulin in a dose-dependent manner. ferulenol altered the normal nuclear morphology of mcf-7 cells. treatment with ferulenol (100 nm and 1 μm) for 24h induced a dose-dependent reduction of cell viability [3]
in vivo
in albino mice, the acute ld50s of ferulenol by single po or ip were 2,100 and 319 mg/kg bw, respectively. three days after ferulenol administration, dosed animals showed hypoprothrombinemia with internal and external hemorrhages. male mice were more sensitive to intoxication than females [4].
storage
+4°C
References
[1] lamnaouer d, bodo b, martin m t, et al. ferulenol and ω-hydroxyferulenol, toxic coumarins from ferula communis var. genuina[j]. phytochemistry, 1987, 26(6): 1613-1615.
[2] e. mamoci, i. cavoski, v. simone, et al. chemical composition and in vitro activity of plant extracts from ferula communis and dittrichia viscosa against postharvest fungi. molecules 16(3), 2609-2625 (2011).
[3] bocca c, gabriel l, bozzo f, et al. microtubule-interacting activity and cytotoxicity of the prenylated coumarin ferulenol[j]. planta medica, 2002, 68(12): 1135-1137.
[4] fraigui o, lamnaouer d, faouzi m y. acute toxicity of ferulenol, a 4-hydroxycoumarin isolated from ferula communis l[j]. veterinary and human toxicology, 2002, 44(1): 5-7.
FERULENOL Preparation Products And Raw materials
Raw materials
Preparation Products
FERULENOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32265 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22855 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9803 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8140 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29774 | 58 |