Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
- CAS No.
- 1149-23-1
- Chemical Name:
- Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
- Synonyms
- diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;DILUDINE;hantzschester;ethidine;1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER;1,4-dihydro-2,6-dimethyL;rr116;etidin;diethone;DIETHANE
- CBNumber:
- CB4757520
- Molecular Formula:
- C13H19NO4
- Molecular Weight:
- 253.29
- MDL Number:
- MFCD00005951
- MOL File:
- 1149-23-1.mol
- MSDS File:
- SDS
Melting point | 178-183 °C(lit.) |
---|---|
Boiling point | 351.8±42.0 °C(Predicted) |
Density | 1.104±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Soluble in organic solvents. |
pka | 3.50±0.70(Predicted) |
form | Solid |
color | Yellow |
λmax | 374nm(EtOH)(lit.) |
InChI | InChI=1S/C13H19NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h14H,5-7H2,1-4H3 |
InChIKey | LJXTYJXBORAIHX-UHFFFAOYSA-N |
SMILES | C1(C)NC(C)=C(C(OCC)=O)CC=1C(OCC)=O |
CAS DataBase Reference | 1149-23-1(CAS DataBase Reference) |
FDA UNII | GWN6123BUG |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | US7970100 | |||||||||
HS Code | 29333990 | |||||||||
Toxicity | LD50 oral in dog: > 12gm/kg | |||||||||
NFPA 704 |
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Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate price More Price(50)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 120227 | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 95% | 1149-23-1 | 1G | $73.8 | 2024-03-01 | Buy |
Sigma-Aldrich | 120227 | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 95% | 1149-23-1 | 10G | $455 | 2024-03-01 | Buy |
Sigma-Aldrich | 120227 | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 95% | 1149-23-1 | 50G | $1870 | 2024-03-01 | Buy |
TCI Chemical | D3775 | Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate >98.0%(HPLC)(N) | 1149-23-1 | 5g | $24 | 2024-03-01 | Buy |
TCI Chemical | D3775 | Diethyl 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate >98.0%(HPLC)(N) | 1149-23-1 | 25g | $59 | 2024-03-01 | Buy |
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Chemical Properties,Uses,Production
Chemical Properties
Light green solid
Uses
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is a hydrogen source in conjugate reduction and organocatalytic reductive amination. It is used as a hydrogen source in organocatalytic reductive amination and conjugate reduction.
Uses
3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine is a dihydropyridine derivative that have been tested for antimicrobial activities.
Application
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DTP) was used to study the mechanism of electrochemical oxidation of DTP in ethanol/water solutions on a glassy carbon electrode.
Hazard
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Toxicology
rat LD50 intraperitoneal >16 gm/kg
mouse LD50 oral >32 gm/kg
mouse LD50 intraperitoneal >30 gm/kg
dog LD50 oral >12 gm/kg
Synthesis
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is prepared by the reaction of formaldehyd and ethyl acetoacetate in the presence of an inert gas.
Purification Methods
recrystallization from EtOH or flash chromatography with petroleum/ethyl acetate (7:3)
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8806 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3882 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12832 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5889 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10986 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 970 | 58 |
Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 +86-18239973690 | sales@suikangpharm.com | China | 311 | 58 |
Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3002 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29793 | 60 |
View Lastest Price from Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2025-01-13 | Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
1149-23-1
|
US $0.00 / kg | 25kg | 99.0% | 1tons | Henan Suikang Pharmaceutical Co.,Ltd. | ||
2025-01-13 | Diloxanidefuroate
1149-23-1
|
US $50.00 / kg | 1kg | 99% | 2000kg | hebei hongtan Biotechnology Co., Ltd | ||
2025-01-13 | Dihydropyridine
1149-23-1
|
US $180.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
- Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
1149-23-1
- US $0.00 / kg
- 99.0%
- Henan Suikang Pharmaceutical Co.,Ltd.
- Diloxanidefuroate
1149-23-1
- US $50.00 / kg
- 99%
- hebei hongtan Biotechnology Co., Ltd
- Dihydropyridine
1149-23-1
- US $180.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd