| Identification | More | [Name]
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate | [CAS]
1149-23-1 | [Synonyms]
1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER
2,6-DIMETHYL-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID DIETHYL ESTER
2,6-dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine
3,5-BIS(CARBOETHOXY)-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE
3,5-DICARBETHOXY-2,6-DIMETHYL-1,4-DIHYDROPYRIDINE
AURORA 4780
DIETHYL 1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATE
DIETHYL 2,6-DIMETHYL-1,4-DIHYDRO-3,5-PYRIDINEDICARBOXYLATE
DIETHYL 2,6-DIMETHYL-1,4-DIHYDROPYRIDINEDICARBOXYLATE
DILUDINE
RARECHEM AQ NN 0171
5-pyridinedicarboxylicacid,1,4-dihydro-2,6-dimethyl-diethylester
diethone
ethidine
etidin
hantzsch’sdihydropyridine
hantzschester
rr116
diethyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate
Dihydropyridinum | [EINECS(EC#)]
214-561-6 | [Molecular Formula]
C13H19NO4 | [MDL Number]
MFCD00005951 | [Molecular Weight]
253.29 | [MOL File]
1149-23-1.mol |
| Chemical Properties | Back Directory | [Melting point ]
178-183 °C(lit.)
| [Boiling point ]
351.8±42.0 °C(Predicted) | [density ]
1.104±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Soluble in organic solvents. | [form ]
Solid | [pka]
3.50±0.70(Predicted) | [color ]
Yellow | [λmax]
374nm(EtOH)(lit.) | [InChI]
InChI=1S/C13H19NO4/c1-5-17-12(15)10-7-11(13(16)18-6-2)9(4)14-8(10)3/h14H,5-7H2,1-4H3 | [InChIKey]
LJXTYJXBORAIHX-UHFFFAOYSA-N | [SMILES]
C1(C)NC(C)=C(C(OCC)=O)CC=1C(OCC)=O | [CAS DataBase Reference]
1149-23-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
2
| [RTECS ]
US7970100
| [HS Code ]
29333990 | [Toxicity]
LD50 oral in dog: > 12gm/kg |
| Hazard Information | Back Directory | [Chemical Properties]
Light green solid | [Uses]
3,5-Dicarboethoxy-2,6-dimethyl-1,4-dihydropyridine is a dihydropyridine derivative that have been tested for antimicrobial activities. | [Application]
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate (DTP) was used to study the mechanism of electrochemical oxidation of DTP in ethanol/water solutions on a glassy carbon electrode. | [Hazard]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] | [Toxicology]
rat LD50 intraperitoneal >16 gm/kg
mouse LD50 oral >32 gm/kg
mouse LD50 intraperitoneal >30 gm/kg
dog LD50 oral >12 gm/kg | [Synthesis]
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate is prepared by the reaction of formaldehyd and ethyl acetoacetate in the presence of an inert gas.
 | [Purification Methods]
recrystallization from EtOH or flash chromatography with petroleum/ethyl acetate (7:3) |
| Spectrum Detail | Back Directory | [Spectrum Detail]
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)MS
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)1HNMR
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)IR1
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate(1149-23-1)IR2
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