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ChemicalBook >> CAS DataBase List >>REVEROMYCIN A

REVEROMYCIN A

CAS No.
134615-37-5
Chemical Name:
REVEROMYCIN A
Synonyms
REVEROMYCIN A;ZESGNAJSBDILTB-OXVOKJAASA-N;Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester
CBNumber:
CB4443481
Molecular Formula:
C36H52O11
Molecular Weight:
660.79
MDL Number:
MFCD00912537
MOL File:
134615-37-5.mol
MSDS File:
SDS
Last updated:2025-04-28 21:36:36

REVEROMYCIN A Properties

Boiling point 849.0±65.0 °C(Predicted)
Density 1.21±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMF: soluble
form solid
pka 4.36±0.17(Predicted)
color tan

SAFETY

Risk and Safety Statements

WGK Germany  3

REVEROMYCIN A price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R0654 Reveromycin A solid 134615-37-5 100μg $341 2024-03-01 Buy
Cayman Chemical 17458 Reveromycin A ≥99% 134615-37-5 250μg $353 2024-03-01 Buy
Cayman Chemical 17458 Reveromycin A ≥99% 134615-37-5 1mg $704 2024-03-01 Buy
TRC R279910 Reveromycin A 134615-37-5 250μg $305 2021-12-16 Buy
Usbiological 464650 Reveromycin A 134615-37-5 100μg $453 2021-12-16 Buy
Product number Packaging Price Buy
R0654 100μg $341 Buy
17458 250μg $353 Buy
17458 1mg $704 Buy
R279910 250μg $305 Buy
464650 100μg $453 Buy

REVEROMYCIN A Chemical Properties,Uses,Production

Uses

Reveromycin A is a spiroketal antibiotic inhibitor of EGF mitogenic activity. Inhibits the signal transduction of the epidermal growth factor. May be used

Uses

Reveromycin A, the dominant analogue of a complex of spiroketals isolated from a Streptomyces sp., is an inhibitor of the mitogenic activity of EGF. Reveromycin A is a G1 phase cell cycle inhibitor, selectively inhibiting isoleucyl-tRNA synthetase. Reveromycin A displays antiproliferative behaviour against human cell lines KB and K562, as well as potent antifungal activity. More recently it has been shown to induce apoptosis in osteoclasts thus inhibiting bone resorption.

in vivo

Reveromycin A (20 mg/kg; twice daily; i.v.; for 3 days) significantly decreases numbers of OCs without affecting numbers of osteoblasts in normal 4-week-old male Sprague-Dawley rats[2].

REVEROMYCIN A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 65)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 		+1-631-485-4226 inquiry@bocsci.com United States 19552 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32268 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4720 55
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12306 58
Lynnchem 86-(0)29-85992781 17792393971 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890 info@novachemistry.com United Kingdom 4381 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58

View Lastest Price from REVEROMYCIN A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Reveromycin A pictures 2025-04-28 Reveromycin A
134615-37-5
 US $1760.00 / mg 10g TargetMol Chemicals Inc.
REVEROMYCIN A ZESGNAJSBDILTB-OXVOKJAASA-N Butanedioic acid, 1-[(2S,3R,6S,8R,9S)-3-butyl-8-[(2E,4E,6S,7S,8E)-9-carboxy-6-hydroxy-3,7-dimethyl-2,4,8-nonatrien-1-yl]-2-[(1E,3E)-4-carboxy-3-methyl-1,3-butadien-1-yl]-9-methyl-1,7-dioxaspiro[5.5]undec-3-yl] ester 134615-37-5 C36H52O11 BioChemical Antibiotics Antibiotics A to Z Antibiotics N-S Epidermal Growth Factor Receptor (EGFR)Antibiotics Interferes with Protein Synthesis Antibiotics Antibiotics A to Antibiotics by Application Antibiotics N-SAntibiotics AntifungalAntibiotics Mechanism of Action Receptor Tyrosine Kinase Inhibitors Spectrum of Activity Antineoplastic and Immunosuppressive AntibioticsReceptor Tyrosine Kinase Biology