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ChemicalBook >> CAS DataBase List >>OBIDOXIME CHLORIDE

OBIDOXIME CHLORIDE

CAS No.
114-90-9
Chemical Name:
OBIDOXIME CHLORIDE
Synonyms
bh6;luh6;bu-6;lueh6;D009768;Obidoxim;luh(sub6);toxobidin;TOXOGONIN;Obidoxime
CBNumber:
CB4312572
Molecular Formula:
C14H16Cl2N4O3
Molecular Weight:
359.21
MDL Number:
MFCD00038864
MOL File:
114-90-9.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

OBIDOXIME CHLORIDE Properties

Melting point 216-219oC dec.
storage temp. -20°C Freezer
solubility Methanol (Slightly), Water (Slightly)
form powder or crystals
color Off-White to Light Beige
BRN 4117377
Stability Stable. Incompatible with strong oxidizing agents.
FDA UNII 3HXR312Z9M
ATC code V03AB13
UNSPSC Code 41116107
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  2
RTECS  UU6825000
Toxicity LD50 in mice, rats (mg/kg): 70, 133 i.v.; 150, 225 i.p.; >2240, >4000 orally; in mice (mg/kg): 172 i.m. (Erdman, Engelhard)

OBIDOXIME CHLORIDE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 74593 Obidoxime chloride analytical standard 114-90-9 25mg $168 2024-03-01 Buy
Sigma-Aldrich 51063 Obidoxime chloride ≥95.0% (HPLC) 114-90-9 1g $407.4 2024-03-01 Buy
TRC O100000 Obidoxime chloride 114-90-9 10g $1295 2021-12-16 Buy
Medical Isotopes, Inc. 29618 Obidoxime chloride >95% 114-90-9 10g $2620 2021-12-16 Buy
American Custom Chemicals Corporation API0000731 OBIDOXIME CHLORIDE 95.00% 114-90-9 10G $2833.1 2021-12-16 Buy
Product number Packaging Price Buy
74593 25mg $168 Buy
51063 1g $407.4 Buy
O100000 10g $1295 Buy
29618 10g $2620 Buy
API0000731 10G $2833.1 Buy

OBIDOXIME CHLORIDE Chemical Properties,Uses,Production

Chemical Properties

White Crystalline Solid

Originator

Toksobidin,Polfa-Starogard

Uses

antibacterial

Uses

Obidoxime Chloride is a cholinesterase reactivator.

Manufacturing Process

2 Methods of producing of obidoxime chloride: 1. Into a boiling agitated solution of 2.44 g pyridine-4-aldoxime in 10 ml absolute ethanol is added dropwise during the course of 25 min a solution of 1.14 g bis-chloromethyl ether in 5 ml absolute ethanol. The reaction mixture is then refluxed for 35 min, and then agitated for 5 h at room temperature. The precipitate of bis-[4-hydroxyimino-methyl-pyridinium-(1)-methyl]-ether Trade dichloride is thoroughly washed with absolute acetone. The yield is 3.5 g which is 98% of the theoretical, and the melting point is 229°C. If convenient, the mother liquor can be reused to make additional product.
2. 12.2 g (0.1 mole) pyridine-4-aldoxime are dissolved with heating in 125 ml chloroform. Within 25 min, 8.5 g (0.075 mole), α,α-dichlorodimethyl ether in 20 ml chloroform are dropped while stirring into the boiling solution. The reaction mixture is heated for another 35 min. After standing for several hours, the precipitate is filtered off, washed with absolute ethanol, acetone and ether and dried at 80°C. Yield: 17.0 g, 95% of the theoretical, and the melting point is 225°C (dec.).

Therapeutic Function

Antidote

General Description

active agent in Toxogonin

Biochem/physiol Actions

Antidote for organophosphate nerve agent poisoning, but, as with other oxime agents, not full spectrum. Obidoxime fails primarily to reactivate acetylcholinesterase that has been inhibited with cyclosarin.

Safety Profile

Poison by intraperitoneal,intravenous, intramuscular, and subcutaneous routes.Moderately toxic by ingestion. When heated todecomposition it emits toxic fumes of Cl- and NOx. Seealso BROMIDES.

OBIDOXIME CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

OBIDOXIME CHLORIDE Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		+86 18953170293 sales@sdzschem.com China 2930 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32202 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-89586680 +86-18192503167 1026@dideu.com China 7859 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551 sales@afinechem.com China 15393 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52849 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490 info@gihichemicals.com China 49984 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501 product@acmec-e.com China 33338 58
Shanghai Likang New Materials Co., Limited 		+86-16631818819 +86-17736933208 3684455296@qq.com China 9300 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580 cooperation@kean-chem.com China 40066 58
J & K SCIENTIFIC LTD. 18210857532 jkinfo@jkchemical.com China 96815 76

View Lastest Price from OBIDOXIME CHLORIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
OBIDOXIME CHLORIDE pictures 2025-04-17 OBIDOXIME CHLORIDE
114-90-9
 US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
Obidoxime dichloride pictures 2024-10-24 Obidoxime dichloride
114-90-9
 US $698.00-370.00 / mg 10g TargetMol Chemicals Inc.
bis(isonicotinaldoxime1-methyl)etherdichloride bu-6 etherbis-14-hydroxy-iminomethylopyridine-(1)-metylodichloride lueh6 luh(sub6) luh(sub6)-cl2 luh(sup6)-cl(sup2) luh6 luh6-chloride luh6dichloride n,n-dimethyleneoxidebis(pyridinium-4-aldoxime)dichloride n,n-dimethylenoxid-bis-(pyridinium-4-aldoxim)-dichlorid obidoximedichloride obidoximehydrochloride pyridinium,1,1’-(oxydimethylene)bis(4-formyl-,dichloride,dioxime toksobidin toxobidin BIS(4-FORMYLPYRIDINIOMETHYL) ETHER DIOXIME 1,1'[OXYBIS(METHYLENE)]-BIS[4-(HYDROXYIMINO)METHYL]PYRIDINIUM DICHLORIDE 1,1'-(OXYDIMETHYLENE)BIS(PYRIDINIUM-4-CARBALDOXIME) DICHLORIDE OBIDOXIME CHLORIDE TOXOGONIN 1,1’-(oxybis(methylene))bis(4-((hydroxyimino)methyl)-pyridiniudichloride 1,1’-(oxydimethylene)bis(4-formylpyridinium)dichloridedioxime toxogonindichloride toxogonine Obidoxime dihydrochloride Obidoxime 1,3-bis(4-aldoximinopyridinium)dimethyletherbichloride 1,3-bis(4-hydroxyiminomethyl-1-pyridinio)-2-oxapropanedichloride bh6 bis(4-hydroxyiminomethylpyridinium-1-methyl)etherdichloride 1,1’-(oxydimethylene)bis(4-formylpyridinium)dioximedichloride 1,1’-[oxybis(methylene)]bis[4-[(hydroxyimino)methyl]-pyridiniudichloride Chloride, obidoxime D009768 Merck brand of obidoxime chloride Obidoxim Pyridinium, 1,1'-(oxybis(methylene))bis(4-((hydroxyimino)methyl))-, dichloride oxo-[[1-[[4-(oxoazaniumylmethylidene)pyridin-1-yl]methoxymethyl]pyridin-4-ylidene]methyl]azanium dichloride OBIDOXIME CHLORIDE USP/EP/BP 1,1'-(Oxybis(methylene))bis(4-((hydroxyimino)methyl)pyridin-1-ium) chloride Obidoxime ChlorideQ: What is Obidoxime Chloride Q: What is the CAS Number of Obidoxime Chloride Q: What is the storage condition of Obidoxime Chloride Q: What are the applications of Obidoxime Chloride 114-90-9 C14H14N4O32HCl Biochemicals and Reagents BioChemical Organic Covalent Modifiers Enzyme Inhibitors by Type Enzymes, Inhibitors, and Substrates Enzyme Inhibitors Activators Intermediates & Fine Chemicals Pharmaceuticals FURADANTIN