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ChemicalBook >> CAS DataBase List >>INDEX NAME NOT YET ASSIGNED

INDEX NAME NOT YET ASSIGNED

CAS No.
2718170-45-5
Chemical Name:
INDEX NAME NOT YET ASSIGNED
Synonyms
RECQL5-IN-1
CBNumber:
CB410906017
Molecular Formula:
C25H18F6N4O2S
Molecular Weight:
552.5
MDL Number:
MOL File:
2718170-45-5.mol
Last updated:2024-10-23 13:36:13

INDEX NAME NOT YET ASSIGNED Properties

Density 1.47±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka 10.92±0.46(Predicted)
color White to off-white

INDEX NAME NOT YET ASSIGNED Chemical Properties,Uses,Production

Biological Activity

RECQL5-IN-1 (Compound 4a) acts as an orally effective RECQL5 inhibitor (targeting both enzymatic and nonenzymatic domain). RECQL5-IN-1 is a potent inhibitor of RECQL5 helicase activity (IC50=46.3 nM). RECQL5-IN-1 inhibits RECQL5-WT cells and RECQL5-KO2 cells with IC50s of 4.8 μM and 19.6 μM, respectively. RECQL5-IN-1 can be used for the research of breast cancer[1].

References

[1]. Saikat Chakraborty, et al. Targeting RECQL5 Functions, by a Small Molecule, Selectively Kills Breast Cancer in Vitr o and in Vivo. J Med Chem. 2021 Feb 11;64(3):1524-1544.

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

INDEX NAME NOT YET ASSIGNED Suppliers

Global( 3)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+8613564774135 zijue.cai@tsbiochem.com United States 19881 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19699 58

View Lastest Price from INDEX NAME NOT YET ASSIGNED manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
RECQL5-IN-1 pictures 2024-10-24 RECQL5-IN-1
2718170-45-5
US $1310.00-2730.00 / mg 10g TargetMol Chemicals Inc.
  • RECQL5-IN-1 pictures
  • RECQL5-IN-1
    2718170-45-5
  • US $1310.00-2730.00 / mg
  • TargetMol Chemicals Inc.
RECQL5-IN-1 2718170-45-5 C25H18F6N4O2S