| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:RECQL5-IN-1
CAS:2718170-45-5
Purity:95.00% Package:2mg;25mg;50mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:RECQL5-IN-1
CAS:2718170-45-5
Package:2mg/RMB 2210;25mg/RMB 11700;50mg/RMB 15197
|
INDEX NAME NOT YET ASSIGNED manufacturers
- RECQL5-IN-1
-
- $1310.00 / 25mg
-
2024-10-24
- CAS:2718170-45-5
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | INDEX NAME NOT YET ASSIGNED Basic information |
| | INDEX NAME NOT YET ASSIGNED Chemical Properties |
| density | 1.47±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | form | Solid | | pka | 10.92±0.46(Predicted) | | color | White to off-white |
| | INDEX NAME NOT YET ASSIGNED Usage And Synthesis |
| Biological Activity | RECQL5-IN-1 (Compound 4a) acts as an orally effective RECQL5 inhibitor (targeting both enzymatic and nonenzymatic domain). RECQL5-IN-1 is a potent inhibitor of RECQL5 helicase activity (IC50=46.3 nM). RECQL5-IN-1 inhibits RECQL5-WT cells and RECQL5-KO2 cells with IC50s of 4.8 μM and 19.6 μM, respectively. RECQL5-IN-1 can be used for the research of breast cancer[1]. | | References | [1]. Saikat Chakraborty, et al. Targeting RECQL5 Functions, by a Small Molecule, Selectively Kills Breast Cancer in Vitr o and in Vivo. J Med Chem. 2021 Feb 11;64(3):1524-1544. |
| | INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials |
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