UNCARINE D
- CAS No.
- 4697-68-1
- Chemical Name:
- UNCARINE D
- Synonyms
- Nsc113094;Uncarin D;UNCARINE D;SPECIOPHYLLINE;Speciophylline (Uncarine D);(3β,7S,20α)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester;Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aR,10'aS)-
- CBNumber:
- CB1202115
- Molecular Formula:
- C21H24N2O4
- Molecular Weight:
- 368.43
- MDL Number:
- MFCD03788765
- MOL File:
- 4697-68-1.mol
- MSDS File:
- SDS
Melting point | 183~184℃ |
---|---|
Boiling point | 555.2±50.0 °C(Predicted) |
Density | 1.33 |
pka | 13.56±0.60(Predicted) |
FDA UNII | ET6RF2PE1P |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H300 |
Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
UNCARINE D price More Price(1)
UNCARINE D Chemical Properties,Uses,Production
Description
One of the alkaloids isolated from the leaves of Mitragyna speciosa, the structure of the base has been determined from the NMR spectrum which demonstrates that the alkaloid has a cis DIE ring junction and a conformation such that the oxindole ring deshields the ester methoxyl group.
Uses
Uncarine D is a compound extracted from Uncaria tomentosa leaves. The compounds extracted from these leaves have exhibited immunomodulating, antiinflammatory and anti-cancer activity, attributed to the presence of tetra/pentacyclic oxindole alkaloids.
Definition
ChEBI: Uncarine D is a member of indolizines.
References
Beckett et al., Sci. Pharm., Froc., 25th (1965)
UNCARINE D Preparation Products And Raw materials
UNCARINE D Suppliers
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