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ChemicalBook >> CAS DataBase List >>Notoginsenoside R1

Notoginsenoside R1

CAS No.
80418-24-2
Chemical Name:
Notoginsenoside R1
Synonyms
Sanchinoside R1;NOTOGINSENOSIDE;NOTOGINSENOSIDE R1;Notoginsenoside Fb;Sanqi glucoside R1;Notoginseng extracts;Notoginsenoside R1-RM;NOTOGINSENOSIDE R1(SH);Notoginseng saponin R1;Notoginsenoside R1 ,98%
CBNumber:
CB0164186
Molecular Formula:
C47H80O18
Molecular Weight:
933.14
MDL Number:
MFCD00210535
MOL File:
80418-24-2.mol
MSDS File:
SDS
Last updated:2025-01-26 16:19:35

Notoginsenoside R1 Properties

Melting point 215～217℃
Boiling point 1010.5±65.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility H2O: soluble1mg/mL, clear, colorless
pka 12.85±0.70(Predicted)
form powder
color white to off-white
biological source Panax notoginseng (Burk.) F.H.Chen
Water Solubility H2O: 1mg/mL, clear, colorless
InChIKey LLPWNQMSUYAGQI-OOSPGMBYSA-N
LogP 1.354 (est)
FDA UNII Z62692362Z

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
WGK Germany  3
HS Code  29389090
Hazardous Substances Data 80418-24-2(Hazardous Substances Data)

Notoginsenoside R1 price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N3915 Notoginsenoside R1 ≥98% (HPLC) 80418-24-2 10mg $140 2024-03-01 Buy
Sigma-Aldrich N3915 Notoginsenoside R1 ≥98% (HPLC) 80418-24-2 50mg $1020 2023-06-20 Buy
TCI Chemical N1129 Notoginsenoside R1 >98.0%(HPLC) 80418-24-2 50mg $141 2024-03-01 Buy
TCI Chemical N1129 Notoginsenoside R1 >98.0%(HPLC) 80418-24-2 10mg $95 2022-04-27 Buy
Cayman Chemical 29691 Notoginsenoside R1 80418-24-2 5mg $72 2024-03-01 Buy
Product number Packaging Price Buy
N3915 10mg $140 Buy
N3915 50mg $1020 Buy
N1129 50mg $141 Buy
N1129 10mg $95 Buy
29691 5mg $72 Buy

Notoginsenoside R1 Chemical Properties,Uses,Production

Description

Notoginsenoside R1 is a ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a disaccharide derivative, a ginsenoside, a tetracyclic triterpenoid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

Uses

Notoginsenoside R1 is an active ingredient isolated from Panax notoginseng that induces tissue-type plasminogen activator synthesis in cultured human umbilical vein endothelial cells.

Application

Notoginsenoside R1 has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an apoptosis inducer and a phytoestrogen. 

Uses

Notoginsenoside R1 acts as an anti-inflammatory agent, inhibiting TNF-α induced PAI-1 production in aortic smooth muscle cells in humans.

Definition

ChEBI: Notoginsenoside R1 is a ginsenoside found in Panax notoginseng that is dammarane which is substituted by hydroxy groups at the 3beta, 6alpha, 12beta and 20 pro-S positions, in which the hydroxy groups at positions 6 and 20 have been converted to the corresponding beta-D-xylopyranosyl-(1->2)-beta-D-glucopyranoside and beta-D-glucopyranoside respectively, and in which a double bond has been introduced at the 24-25 position. It has a role as a plant metabolite, an antioxidant, a neuroprotective agent, an apoptosis inducer and a phytoestrogen. It is a beta-D-glucoside, a 12beta-hydroxy steroid, a 3beta-hydroxy steroid, a disaccharide derivative, a ginsenoside, a tetracyclic triterpenoid and a 3beta-hydroxy-4,4-dimethylsteroid. It derives from a hydride of a dammarane.

Biological Activity

Notoginsenoside R1 has been shown to exhibit antooxidant, anti-inflammatory, antiapoptotic, and immune-stimulatory properties.

Notoginsenoside R1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 307)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+8618829768577 gao490372054@gamil.com China 1249 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 997 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
+86-18791163155 +86-13119157289 13119157289@163.com China 3558 58
Hebei Weibang Biotechnology Co., Ltd 		+8615531157085 abby@weibangbio.com China 8806 58
Hebei Mujin Biotechnology Co.,Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12831 58
Wuhan Quanjinci New Material Co.,Ltd. 		+86-15271838296; +8615271838296 kyra@quanjinci.com China 1512 58
BINBO BIOLOGICAL CO.,LTD 		+8618629063126 info@binbobiological.com China 430 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Shanghai Zheyan Biotech Co., Ltd. 		18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29879 58

View Lastest Price from Notoginsenoside R1 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Panax notoginseng extract pictures 2025-01-23 Panax notoginseng extract
80418-24-2
 US $0.00 / KG 1KG ≥98% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Notoginsenoside R1 pictures 2025-01-23 Notoginsenoside R1
80418-24-2
 US $0.00 / KG 1KG 80% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Notoginsenoside R1 pictures 2025-01-16 Notoginsenoside R1
80418-24-2
 US $120.00 / kg 1kg 99% 23000000 tons Wuhan Quanjinci New Material Co.,Ltd.
  • Notoginsenoside R1 pictures
  • Notoginsenoside R1
    80418-24-2
  • US $0.00 / KG
  • 80% HPLC
  • Changsha Staherb Natural Ingredients Co., Ltd.
(3β,6α,12β)-20-(β-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl-β-D-glucopyranoside Notoginsenoside Fb NOTOGINSENOSIDE R1 NOTOGINSENOSIDE R1(SH) NOTOGINSENOSIDE glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl2-O-β-D-xylopyranosyl- Sanchinoside R1 Notoginsenoside R1，Sanchinoside R1 Notoginsenoside R1 ,98% TIANFU-CHEM Notoginsenoside R1 (2S,3R,4S,5S,6R)-2-[(2S)-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol (3beta,6alpha,12beta)-20-(beta-D-Glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-beta-D-Xylopyranosyl-beta-D-glucopyranoside β-D-Glucopyranoside, (3β,6α,12β)-20-(β-D-glucopyranosyloxy)-3,12-dihydroxydammar-24-en-6-yl 2-O-β-D-xylopyranosyl- Notoginsenoside R1 Standard Notoginseng extracts 2-[2-[6-[[4,5-dihydroxy-6-(hydroxymethyl)-3-methyl-2-oxanyl]oxy]-3,12-dihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methylhept-5-en-2 Sanqi glucoside R1 Notoginsenoside R1, 98%, from Panax notoginseng (Burk.)F.H.Chen Panax notoginseng saponin R1 (2S,3R,4S,5S,6R)-2-(((S)-2-((3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-6-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-3,12-dihydroxy-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-6-methylhept-5-en-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol Notoginseng saponin R1 Notoginseng saponin FP2 Panax Notoginseng Saponins, PNS Notoginsenoside R1-RM Notoginsenoside R1 Impurity Notoginsenoside R1, 10 mM in DMSO 80418-24-2 C47H80O18 chemical reagent Inhibitors pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract