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Quinagolide hydrochloride

Quinagolide hydrochloride Struktur
94424-50-7
CAS-Nr.
94424-50-7
Englisch Name:
Quinagolide hydrochloride
Synonyma:
SDZ 205-502;CV205-502 hydrochloride;Norprolac Hydrochloride;QUINAGOLIDE HYDROCHLORIDE;Quinagolide hydrochloride (CV205-502 hydrochloride);(3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride;rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride;(3α,4aα,10aβ)-N,N-Diethyl-N'- (1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride;(+/-)-N,N-diethyl-N'-<(3α,4aα,10aβ)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzoquinolinyl>sulfamide hydrochloride
CBNumber:
CB9995839
Summenformel:
C20H34ClN3O3S
Molgewicht:
432.02
MOL-Datei:
94424-50-7.mol

Quinagolide hydrochloride Eigenschaften

Schmelzpunkt:
234-236°
storage temp. 
Store at -20°C
L?slichkeit
DMSO : ≥ 43 mg/mL (99.53 mM)
Aggregatzustand
Solid
Farbe
White to off-white
CAS Datenbank
94424-50-7(CAS DataBase Reference)

Sicherheit

Quinagolide hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Quinagolide is a potent and specific non-ergot dopamine D2 agonist launched in the Netherlands for the treatment of hyperprolactinemia. Quinagolide is effective in inhibiting prolactin secretion by human pituitary tumor and hyperprolactinemia in vitro and in viva A daily dose of as low as 60 pg is able to achieve a pronounced and prolonged suppressive effect on serum prolactin and growth hormone secretion. It is also effective in providing relief from associated effects such as infertility, galactorrhea, oligomenorrhea, amenorrhea, loss of IibMo and impotence. Compared with the most widely used antiprolactin, bromocriptine, quinagolide is more potent in vivo with a longer duration of action and fewer side effects. A recent study showed that acute administration of quinagolide suppresses growth hormone secretion in acromegalic patients and thus could serve as an alternative therapy in acromegaly.

Verwenden

Quinagolide is a nonergot dopamine D2-receptor agonist. Quinagolide acts as an prolactin inhibitor.

Quinagolide hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Quinagolide hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 37)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32080 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15354 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38470 58
Amadis Chemical Company Limited
571-89925085
sales@amadischem.com China 131957 58
Mainchem Co., Ltd. +86-0592-6210733
sale@mainchem.com China 32343 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
Chembest Research Laboratories Limited +86-21-20908456
sales@BioChemBest.com China 6005 61
LGM Pharma 1-(800)-881-8210
inquiries@lgmpharma.com United States 2123 70

94424-50-7()Verwandte Suche:


  • QUINAGOLIDE HYDROCHLORIDE
  • (3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride
  • (3α,4aα,10aβ)-N,N-Diethyl-N'- (1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride
  • Norprolac Hydrochloride
  • rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride
  • SDZ 205-502
  • Quinagolide hydrochloride (CV205-502 hydrochloride)
  • (+/-)-N,N-diethyl-N'-<(3α,4aα,10aβ)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzoquinolinyl>sulfamide hydrochloride
  • CV205-502 hydrochloride
  • 94424-50-7
  • C20H34ClN3O3S
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
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