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Metomidat

metomidate  Struktur
5377-20-8
CAS-Nr.
5377-20-8
Bezeichnung:
Metomidat
Englisch Name:
metomidate
Synonyma:
EM-01;Hypnodil;AquacalM;MethoxyMol;metomidate;Methomidate;MethoxyMol R-7315;Etomidate impurity B CRS;Metomidate in acetonitrile;Etomidate Impurity 2 (Etomidate EP Impurity B)
CBNumber:
CB9913785
Summenformel:
C13H14N2O2
Molgewicht:
230.26
MOL-Datei:
5377-20-8.mol

Metomidat Eigenschaften

Siedepunkt:
372.26°C (rough estimate)
Dichte
1.13
Brechungsindex
1.6450 (estimate)
storage temp. 
Refrigerator
L?slichkeit
Chloroform, Methanol
pka
4.15±0.23(Predicted)
Farbe
Colourless to Pale Yellow
InChI
InChI=1S/C13H14N2O2/c1-10(11-6-4-3-5-7-11)15-9-14-8-12(15)13(16)17-2/h3-10H,1-2H3
InChIKey
FHFZEKYDSVTYLL-UHFFFAOYSA-N
SMILES
C1N(C(C2=CC=CC=C2)C)C(C(OC)=O)=CN=1

Sicherheit

Metomidat Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Colourless Hazy Oil

Verwenden

Metomidate is a the methyl ester analogue of Etomidate (E933300), with sedative and hypnotic properties. Metomidate is mainly used as an anesthetic for veterinary use on its own or in combination with Azaperone (A802200) and other sedatives.

Mechanism of action

Metomidate reduces plasma cortisol and glucose concentrations and increases fish pigmentation, presumably because of increased production of melanocyte-stimulating hormone on the same primary protein as adrenocorticotropic hormone (ACTH). Imidazole anesthetics (e.g., metomidate and etomidate) interrupt cortisol synthesis in mammals by suppressing the enzyme 11-beta-hydroxylase, which is necessary for cortisol production.

Metomidat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

5377-20-8(Metomidat)Verwandte Suche:


  • metomidate
  • 1-(1-Phenylethyl)-1H-imidazole-5-carboxylic acid methyl ester
  • Methomidate
  • 3-(1-phenylethyl)imidazole-4-carboxylic acid methyl ester
  • methyl 3-(1-phenylethyl)imidazole-4-carboxylate
  • Methyl 3-(1-phenylethyl)imidazole-5-carboxylate
  • 1-(α-Methylbenzyl)iMidazole-5-carboxylic Acid Methyl Ester
  • AquacalM
  • Hypnodil
  • MethoxyMol
  • MethoxyMol R-7315
  • Methyl 1-(α-Methylbenzyl)iMidazole-5-carboxylate
  • Methyl 1-[(1RS)-1-phenylethyl]-1H-imidazole-5-carboxylate
  • Etomidate impurity B CRS
  • 1H-Imidazole-5-carboxylic acid, 1-(1-phenylethyl)-, methyl ester
  • Methyl 1-(1-Phenylethyl)-1H-Imidazole-5-Carboxylate
  • Etomidate Impurity 2 (Etomidate EP Impurity B)
  • EM-01
  • Metomidate in acetonitrile
  • 5377-20-8
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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