C6 CERAMIDE
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- CAS-Nr.
- 124753-97-5
- Englisch Name:
- C6 CERAMIDE
- Synonyma:
- C6 CERAMIDE;CERAMIDE C6;06:0 CERAMIDE;CAPROYL CERAMIDE;C8 SPHINGOID BASE;C6-D-ERYTHRO-CERAMIDE;N-HEXANOYLSPHINGOSINE;C6 Ceramide (d18:1/6:0);N-CAPROYL-D-SPHINGOSINE;N-HEXANOY-D-SPHINGOSINE
- CBNumber:
- CB9744617
- Summenformel:
- C24H47NO3
- Molgewicht:
- 397.63
- MOL-Datei:
- 124753-97-5.mol
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C6 CERAMIDE Eigenschaften
- Schmelzpunkt:
- 76-77°C
- Siedepunkt:
- 521.03°C (rough estimate)
- Dichte
- 1.0077 (rough estimate)
- Brechungsindex
- 1.6000 (estimate)
- storage temp.
- -20°C
- L?slichkeit
- Soluble in 100% ethanol at 25mg/ml and also in DMSO at 50mg/ml.
- pka
- 13.53±0.20(Predicted)
- Aggregatzustand
- Powder
- Farbe
- White
- Stabilit?t:
- Freezer -20°C
- LogP
- 7.463 (est)
C6 CERAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Beschreibung
C6 ceramide is a cell-permeable analog of naturally occurring ceramides. With a longer carbon chain than C2 ceramide, it is somewhat more hydrophobic, and may more closely mimic the effects of natural ceramides. C6 ceramide mediates many diverse biological activities including apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain. It also enhances the expression of COX-2 in rat granulosa cells and stimulates the growth of bovine aortic smooth muscle cells. C6 ceramide acts in neuronal axons to inhibit neurite growth.
Chemische Eigenschaften
Off White Powder
Verwenden
C6 Ceramide (d18:1/6:0) has been used as a chemotherapeutic agent to test its anti-tumor effect in breast cancer cells and ovarian cancer cell lines. It has also been used to test chemo-sensitization effects in cancer cells.
Allgemeine Beschreibung
Biologically active, cell-permeable, non-physiological ceramide analog. Induces a dramatic arrest in the G
0/G
1 phase of the cell cycle. Activates MAP kinase. Activates protein phosphatase 2A (PP2A) at 10 nM. Inhibits diacylglycerol accumulation and phospholipase D (PLD) activation in fibroblasts. Induces apoptosis in MOLT-4 leukemia cells.
C6 CERAMIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
C6 CERAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 98)Lieferanten
124753-97-5()Verwandte Suche:
- N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]hexanaMide
- C6 Ceramide (d18:1/6:0)
- N-HEXANOYL-D-ERYTHRO-SPHINGOSINE;C6 CERAMIDE (D18:1/6:0)
- 6-Hexanoyl-D-erythro-sphingosine, 99+%
- C6 ceramide, Caproyl ceramide, N-Caproyl-D-sphingosine
- 6-HEXANOYL-D-ERYTHRO-SPHINGOSINE, SYNTHETICAL, 99+%
- 6-Hexanoyl-D-erythro-sphingosine, synthetical
- 6-Hexanoyl-D-erythro-sphingosine,99+%,synthetical
- 6-Hexanoyl-D-erythro-sphingosineCeramide C6
- CAPROYL CERAMIDE
- C6 CERAMIDE OF D-ERYTHRO-C8-SPHINGOSINE
- C6 CERAMIDE
- C6-D-ERYTHRO-CERAMIDE
- C8 SPHINGOID BASE
- D-ERYTHRO-SPHINGOSINE, N-HEXANOYL-
- 06:0 CERAMIDE
- 6-HEXANOYL-D-ERYTHRO-SPHINGOSINE
- N-CAPROYL-C18-SPHINGOSINE
- N-CAPROYL-D-SPHINGOSINE
- N-HEXANOYL-D-ERYTHRO-SPHINGOSINE
- N-HEXANOY-D-SPHINGOSINE
- N-HEXANOYLSPHINGOSINE
- N-HEXANOYLSPHINGOSINE, D-ERYTHRO
- N-HEXANOYL-D-SPHINGOSINE
- N-HEXANOYL-D-SPHINGOSINE FROM SYNTHETIC D-SPHINGOSINE
- CERAMIDE C6
- alpha-Hydroxyoctadecanoyl-phytosphingosine
- D-erythro-Sphingosine, N-Hexanoyl- - CAS 124753-97-5 - Calbiochem
- Hexanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
- N-((2S,3R,E)-1,3-Dihydroxyoctadec-4-en-2-yl)hexanamide
- 124753-97-5
- C24H47NO3
- BioChemical
- Cancer Research
- Antitumor Agents
- Anti-Proliferative Agents
- Mixed Fatty Acids
- Fatty Acid Derivatives & Lipids
- Glycerols
- Inhibitors
- Protein Kinase Inhibitors and Activators
