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8-M-PDOT

8-M-PDOT Struktur
134865-70-6
CAS-Nr.
134865-70-6
Englisch Name:
8-M-PDOT
Synonyma:
AH 002;8-M-PDOT;8 M PDOT,8MPDOT;8-METHOXY-2-PROPIONAMIDOTETRALIN;Propanamide, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-
CBNumber:
CB9487996
Summenformel:
C14H19NO2
Molgewicht:
233.31
MOL-Datei:
134865-70-6.mol

8-M-PDOT Eigenschaften

Siedepunkt:
447.8±45.0 °C(Predicted)
Dichte
1.09±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
L?slichkeit
Soluble to 50 mM in ethanol and to 100 mM in DMSO
Aggregatzustand
Powder
pka
15.87±0.20(Predicted)
Farbe
White to off-white

Sicherheit

8-M-PDOT Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM). It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 μg/μl) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson''s disease.

Biologische Aktivit?t

Melatonin receptor agonist, 20-fold selective for the MT 2 (vs MT 1 ) subtype. At human recombinant MT 1 and MT 2 receptors, displays pK i values of 8.23 and 8.95 respectively.

8-M-PDOT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


8-M-PDOT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 32)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32080 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38470 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52925 58
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19863 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11217 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278
sales@ubiochem.com China 4297 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223;
psaitong@jm-bio.com China 29774 58

134865-70-6()Verwandte Suche:


  • 8-METHOXY-2-PROPIONAMIDOTETRALIN
  • 8-M-PDOT
  • AH 002
  • 8 M PDOT,8MPDOT
  • Propanamide, N-(1,2,3,4-tetrahydro-8-methoxy-2-naphthalenyl)-
  • 134865-70-6
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