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ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1

ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Struktur
CAS-Nr.
Englisch Name:
ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1
Synonyma:
Anti-CCL2;ANTI-MCAF;Anti-HC11;ANTI-MCP-1;Anti-GDCF-2;Anti-HSMCR30;Anti-GDCF-2 HC11;Anti-C-C motif chemokine 2;Anti-Small-inducible cytokine A2;Anti-Monocyte secretory protein JE
CBNumber:
CB9426153
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
lyophilized powder

Sicherheit

S-S?tze: 22-24/25

ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Monoclonal anti-Monocyte Chemotactic Protein-1 antibody can be used in western blotting.

Allgemeine Beschreibung

C-C motif chemokine ligand 2 (CCL2) gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. (provided by RefSeq).CCL2 is a pro-inflammatory cytokine. It belongs to the family of CC-type chemokines, which can be produced by almost every cells.

Biochem/physiol Actions

C-C motif chemokine ligand 2 (CCL2) plays a critical role in the development of allergic inflammatory reactions by employing immune cells, that is linked to autoimmune diseases. It binds to CC chemokine receptor 2 (CCR2) and regulates monocyte chemotaxis and T-lymphocyte differentiation. The protein recruits monocytes to liver. It is involved in macrophage fusion and foreign body giant cell formation.

ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80

  • ANTI-MONOCYTE CHEMOTATIC AND ACTIVATING FACTOR
  • ANTI-MONOCYTE CHEMOTACTIC PROTEIN-1
  • ANTI-MCAF
  • ANTI-MCP-1
  • ANTI-MCP-1/ACTIVATING FACTOR, HUMAN
  • Anti-Monocyte Chemotactic Protein 1 antibody produced in goat
  • Anti-CCL2
  • Monoclonal Anti-Monocyte Chemotactic Protein-1 antibody produced in mouse
  • Anti-C-C motif chemokine 2
  • Anti-Monocyte chemoattractant protein 1
  • Anti-Monocyte chemotactic and activating factor
  • Anti-Monocyte secretory protein JE
  • Anti-Small-inducible cytokine A2
  • Anti-CCL2 antibody produced in rabbit
  • Anti-GDCF-2
  • Anti-GDCF-2 HC11
  • Anti-HC11
  • Anti-HSMCR30
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