Bendamustine Hydrochloride Monohydrate
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- CAS-Nr.
- 1374784-02-7
- Englisch Name:
- Bendamustine Hydrochloride Monohydrate
- Synonyma:
- Bendamustine HCL Monohydrate;Bendamustine Hydrochloride Monohydrate;4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride hydrate
- CBNumber:
- CB93361787
- Summenformel:
- C16H24Cl3N3O3
- Molgewicht:
- 412.74
- MOL-Datei:
- 1374784-02-7.mol
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Bendamustine Hydrochloride Monohydrate Eigenschaften
- InChI
- InChI=1S/C16H21Cl2N3O2.ClH.H2O/c1-20-14-6-5-12(21(9-7-17)10-8-18)11-13(14)19-15(20)3-2-4-16(22)23;;/h5-6,11H,2-4,7-10H2,1H3,(H,22,23);1H;1H2
- InChIKey
- TWBJYCLUHINEDN-UHFFFAOYSA-N
- SMILES
- CN1C(=NC2=CC(N(CCCl)CCCl)=CC=C12)CCCC(=O)O.Cl.O
Sicherheit
Bendamustine Hydrochloride Monohydrate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Bendamustine hydrochloride monohydrate (marketed as Treanda?) is a nitrogen mustard purine analog alkylator used to treat chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphomas. Bendamustine is a nitrogen mustard drug used to treat chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine causes intra- and inter-strand crosslinks between DNA bases, resulting in cell death. It is active against both active and quiescent cells, although the exact mechanism of action is unknown.
Einzelnachweise
[1] J. Kaduk. “Powder X-ray diffraction of bendamustine hydrochloride monohydrate, C16H22Cl2N3O2Cl·H2O.” Powder Diffraction 34 1 (2018): 74–75.
Bendamustine Hydrochloride Monohydrate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Bendamustine Hydrochloride Monohydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 19)Lieferanten
- 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid hydrochloride hydrate
- Bendamustine Hydrochloride Monohydrate
- Bendamustine HCL Monohydrate
- 1374784-02-7
