(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid is an intermediate used in the synthesis of ent-Abacavir (A105015), which is an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Suzhou ARTK Medchem Co., Ltd.	+86-512-68323658 +86-18168183658	sales1@artkmedchem.com	China	39004	58
PharmaBlock Sciences (Nanjing), Inc.	4000255188 4000255188	sales_china@pharmablock.com	China	9786	58
Jinan elephant international trading co., LTD		13006575422@163.com	China	6355	58
Dezhou LonWel Pharmaceutical Technology Co., Ltd.	13761310616	39324283@qq.com	China	1991	58
Shanghai Haohong Pharmaceutical Co., Ltd.	4008210725 4008210725	malulu@leyan.com	China	54987	58
Nanjing Xiuhe Pharmaceutical Technology Co., Ltd.	19848384152	2643971943@qq.com	China	366	58
Pushan Industry (Shaanxi) Co., Ltd.	029-81310890 13571859809	info@pushanshiye.com	China	10009	58
Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd.	025-66061636 18013972705	qqyang@aikonchem.com	China	10238	58

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• (1R,4S) Methyl 4-aminocyclopent-2-ene-1-carboxylate D-tartrate
• Methyl (1R,4S)-4-Amino-2-cyclopentene-1-carboxylate (2S,3S)-2,3-Dihydroxybutanedioic Acid
• (2S,3S)-2,3-Dihydroxybutanedioic acid methyl (1R,4S)-4-aminocyclopent-2-ene-1-carboxylate
• Peramivir Intermediater 2
• Methyl (1R,4S)-4-Amino-2-cyclopentenecarboxylate (2S,3S)-2,3-Dihydroxysuccinate
• 419563-23-8