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(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Struktur
149690-12-0
CAS-Nr.
149690-12-0
Englisch Name:
(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride
Synonyma:
Sacubitril Impurity 9 HCl;AHU09;LCZ698;LCZ696-5;LCZ696M-01;4S)-ethyl 5-([1;LCZ-696 Impurity 34;LCZ696 Intermediate2;LCZ-696-005-2R4S-HCl;LCZ696 impurities122
CBNumber:
CB92723689
Summenformel:
C20H26ClNO2
Molgewicht:
347.88
MOL-Datei:
149690-12-0.mol

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Eigenschaften

Schmelzpunkt:
155 - 162°C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
Stabilit?t:
Hygroscopic
InChI
InChI=1/C20H25NO2.ClH/c1-3-23-20(22)15(2)13-19(21)14-16-9-11-18(12-10-16)17-7-5-4-6-8-17;/h4-12,15,19H,3,13-14,21H2,1-2H3;1H/t15-,19+;/s3
InChIKey
MYJTZLYRAWUSLB-MTPCZXHRNA-N
SMILES
C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](N)C[C@@H](C)C(=O)OCC.Cl |&1:13,16,r|
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Application

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a Sacubitril intermediate.

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Sacubitril Sodium

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 221)Lieferanten
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149690-12-0()Verwandte Suche:

  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl
  • LCZ696 Intermediate2
  • LCZ698
  • [1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, hydrochloride (1:1), (αR,γS)-
  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate hydrochloride
  • (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride
  • (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1)
  • (2R, 4S) - ethyl 5- ([1,1'- biphenyl]-4- group) -4- amino -2- methyl valerate hydrochloride
  • acubitril Impurity 9 HCl
  • (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride149690-12-0
  • LCZ-696 Impurity 34
  • AHU09
  • LCZ-696-005-2R4S-HCl
  • Sacubitril Impurity 26
  • LCZ696M-01
  • LCZ696(valsartan + sacubitril) impurity 5
  • (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate HCl salt
  • 1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride
  • 4S)-ethyl 5-([1
  • LCZ696-5
  • Ethyl (2R,4S)-5-(4-Biphenylyl)-4-amino-2-methylpentanoate Hydrochloride
  • 1,1'-Biphenyl]-4-pentanoicacid,γ-amino-α-methyl-,ethylester,(αR,γS)-,hydrochloride(1:1)
  • ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride
  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpenta...
  • LCZ696 impurities122
  • ethyl (2R,4S)-4-amino-5-{[1,1'-biphenyl]-4-yl}-2-methylp entanoate hydrochloride
  • Sacubitril Impurity 9 HCl
  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino
  • Benzene,1-methoxy-2-methyl-5-nitro-
  • (2R,4S)-Ethyl 4-amino-5-(biphenyl -4-yl)-2-methylpentanoate hydrochloride
  • Sacubitril Impurity 35 HCl
  • Sacubitril Impurity 26 Hydrochloride
  • SACUBITRIL SAV-3 (AMINE ESTER)
  • Salcubatra calcium impurity D
  • LCZ696 Intermediate 3
  • Sacubitril intermediates(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride
  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride
  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
  • Sacubitril Impurity 3 HCl
  • Olaquindox Impurity 4
  • LCZ-696 Impurity 5 HCl
  • Sacubitril Impurity 5 HCl
  • LCZ696（valsartan + sacubitril） impurity 55(Hydrochloride)
  • 149690-12-0
  • LCZ696
  • 149690-12-0
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