Amino-PEG4-acid
|
|
|
- CAS-Nr.
- 663921-15-1
- Englisch Name:
- Amino-PEG4-acid
- Synonyma:
- 1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid;NH2-PEG4-COOH;Amino-PEG4-acid;NH2-PEG4-CH2CH2COOH;3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid;NH2-PEG4-PA;Amino-PEG4-COOH;AMINE-PEG4-COOH;amino-dPEG4-acid;Amino-dPEGx-acid
- CBNumber:
- CB92501434
- Summenformel:
- C11H23NO6
- Molgewicht:
- 265.3
- MOL-Datei:
- 663921-15-1.mol
|
Amino-PEG4-acid Eigenschaften
- Siedepunkt:
- 409.6±40.0 °C(Predicted)
- Dichte
- 1.134±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.28±0.10(Predicted)
- Aggregatzustand
- powder
- Farbe
- White
- InChI
- InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)
- InChIKey
- DKUZHSDZSMQOGQ-UHFFFAOYSA-N
- SMILES
- C(O)(=O)CCOCCOCCOCCOCCN
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
|
Amino-PEG4-acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
H2N-Dpeg(4)-COOH, can be used in optical imaging of integrin αvβ3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers. Integrin αvβ3 plays great roles in tumor angiogenesis, invasion, and metastasis.
benefits
Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 ?) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (D = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification.
Einzelnachweise
1. Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers. DOI:
10.1021/mp800150r2. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. DOI:
10.1021/bc400050k3. Microwave-mediated synthesis of labeled nucleotides with utility in the synthesis of DNA probes. DOI:
10.1021/bc100013b4. Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers. DOI:
10.1021/bc800455p
Amino-PEG4-acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Amino-PEG4-acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 136)Lieferanten
663921-15-1()Verwandte Suche:
- α-amine-ω-propionic acid tetraethylene glycol
- alpha-aMine-oMega-propionic acid tetraethylene glycol
- H2N-PEG4-CH2CH2COOH
- Amino-dPEGx-acid
- amino-dPEG4-acid
- Amino-PEG4-propionic acid
- AMINE-PEG4-COOH
- Amino-PEG4-COOH
- 3-Amino(peg4)propionic acid
- 3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid
- 1-Amino-3,6,9,12-tetraoxa-15-pentadecanoic Acid
- α-Amine-ω-propionic acid tetraethylene glycol,Amino-PEG4-acid
- Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-
- 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
- α-Amine-ω-propionic acid tetraethylene glycol hydrochloride
- 3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid
- 1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid
- Amino-PEG4-acid
- NH2-PEG4-COOH
- NH2-PEG4-CH2CH2COOH
- H2N-PEG4-CH2CH2COOH/Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-
- NH2-PEG4-PA
- 663921-15-1
- C11H23NO6
- PEG-COOH
- peg
