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Paquinimod

Paquinimod Struktur
248282-01-1
CAS-Nr.
248282-01-1
Englisch Name:
Paquinimod
Synonyma:
ABR25757;ABR-25757;ABR 25757;ABR?215757;Paquinimod;ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.;ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod;ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
CBNumber:
CB92498835
Summenformel:
C21H22N2O3
Molgewicht:
350.41
MOL-Datei:
248282-01-1.mol

Paquinimod Eigenschaften

Siedepunkt:
487.3±45.0 °C(Predicted)
Dichte
1.267±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
DMSO:15.0(Max Conc. mg/mL);42.8(Max Conc. mM)
Aggregatzustand
A solid
pka
4.50±1.00(Predicted)
Farbe
White to off-white
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Paquinimod Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4. Paquinimod reduces pathology in experimental collagenase-induced osteoarthritis. Paquinimod treatment of collagenase-induced OA (CIOA) resulted in significantly reduced synovial thickening (57%), osteophyte size at the medial femur (66%) and cruciate ligaments (67%) and cartilage damage at the medial tibia (47%) and femur (75%; n=7, untreated n=6). Paquinimod reduces leukocyte recruitment during sterile inflammation. Paquinimod also reduced priming of proinflammatory effector CD4(+) T cells.

Paquinimod Upstream-Materialien And Downstream Produkte

Upstream-Materialien

34934-06-0 3-?Quinolinecarboxylic acid, 5-?ethyl-?1,?2-?dihydro-?4-?hydroxy-?1-?methyl-?2-?oxo-?, ethyl ester methyl 5-ethyl-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate 2-AMINO-6-ETHYLBENZOIC ACID N-Ethylanilin

Downstream Produkte

Paquinimod Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 67)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32951 60
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32072 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
Guangzhou TongYi biochemistry technology Co.,LTD 		+8613073028829
 mack@tongyon.com China 2994 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
LEAP CHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 24727 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38465 58

248282-01-1()Verwandte Suche:

  • Paquinimod
  • ABR?215757
  • N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
  • ABR 25757
  • ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1
  • ABR25757
  • ABR-25757
  • ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.
  • N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide
  • 3-Quinolinecarboxamide, N,5-diethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-
  • ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod
  • 248282-01-1
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