3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE
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- CAS-Nr.
- 405911-09-3
- Englisch Name:
- 3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE
- Synonyma:
- GW3965;CS-1391;GW3965
(GW 3965;GW 3965 HYDROCHLORIDE;2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic a;2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic acid;Benzeneacetic acid,3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-;3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE;3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-diphenylethyl)aMino]propvloxy]phenylacetic acid hydrochloride;3-[3-[[[2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]METHYL](2,2-DIPHENYLETHYL)AMINO]PROPOXY]BENZENEACETIC ACID HYDROCHLORIDE
- CBNumber:
- CB9217997
- Summenformel:
- C33H31ClF3NO3
- Molgewicht:
- 582.05
- MOL-Datei:
- 405911-09-3.mol
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3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Eigenschaften
- Schmelzpunkt:
- 174-179°C
- Siedepunkt:
- 672.4±55.0 °C(Predicted)
- Dichte
- 1.261±0.06 g/cm3(Predicted)
- storage temp.
- Desiccate at RT
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 4.18±0.10(Predicted)
- Farbe
- White to Off-White
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
GW3965 can be used in biological study of effect of liver X receptor agonists, T0901317 and GW3965 treatment on cholesterol efflux and apoptosis in human CAL-1 and GEN2.2 blastic plasmacytoid dendritic cell neoplasm cells.
Biologische Aktivit?t
Selective, orally active non-steroidal agonist for the liver X receptor (LXR). In cell-based reporter gene assays, acts as a full agonist of hLXR α and hLXR β (EC 50 values are 190 and 30 nM respectively). Up-regulates ABCA1 gene expression and raises circulating HDL levels. Displays potent antiatherogenic activity in mouse models of atherosclerosis.
3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 54)Lieferanten
- GW3965
- GW 3965 HYDROCHLORIDE
- 3-[3-[N-(2-CHLORO-3-TRIFLUOROMETHYLBENZYL)-(2,2-DIPHENYLETHYL)AMINO]PROPYLOXY]PHENYLACETIC ACID HYDROCHLORIDE
- 3-[3-[[[2-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]METHYL](2,2-DIPHENYLETHYL)AMINO]PROPOXY]BENZENEACETIC ACID HYDROCHLORIDE
- 3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-diphenylethyl)aMino]propvloxy]phenylacetic acid hydrochloride
- 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic a
- 2-(3-(3-((2-Chloro-3-(trifluoromethyl)benzyl)(2,2-diphenylethyl)-amino)propoxy)phenyl)acetic acid
- Benzeneacetic acid,3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-
- CS-1391
- GW3965
(GW 3965
- 405911-09-3
- C33H31ClF3NO3HCl
- C33H31NO3ClF3HCl
- C33H31ClF3NO3
- C33H32Cl2F3NO3
- Inhibitor
