MPEP Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
A potent, subtype selective mGluR5 antagonist
Biologische Aktivit?t
Potent and highly selective non-competitive antagonist at the mGlu 5 receptor subtype (IC 50 = 36 nM) and a positive allosteric modulator at mGlu 4 receptors. Centrally active following systemic administration in vivo . Reverses mechanical hyperalgesia in the inflamed rat hind paw. Also available as part of the Group I mGlu Receptor Tocriset™ .
MPEP Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte