4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Recently, a series of relatively simple compounds were found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. CAY10449 is one of the more potent of these. CAY10449 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a K_i value of about 3 nM. Although CAY10449 was not tested in rats, the related compound CAY10441 shows significant analgesic activity in standard antinociceptive assays.

4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58

---

• CAY10449
• 4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE