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Dimetacrine

Dimetacrine Struktur
4757-55-5
CAS-Nr.
4757-55-5
Englisch Name:
Dimetacrine
Synonyma:
Dimetacrine;dimethacrine;10(9H)-AcridinepropanaMine,N,N,9,9-tetraMethyl-;9,9-Dimethyl-10-[3-(dimethylamino)propyl]acridan;3-(9,9-dimethylacridin-10-yl)propyl-dimethyl-amine;3-(9,9-dimethylacridin-10-yl)-N,N-dimethylpropan-1-amine;3-(9,9-dimethylacridin-10-yl)-N,N-dimethyl-propan-1-amine;9,10-Dihydro-9,9-dimethyl-10-(3-dimethylaminopropyl)acridine
CBNumber:
CB91103240
Summenformel:
C20H26N2
Molgewicht:
294.43
MOL-Datei:
4757-55-5.mol

Dimetacrine Eigenschaften

Siedepunkt:
bp1 200°
Dichte
0.9927 (rough estimate)
Brechungsindex
1.5640 (estimate)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
pka
9.49±0.28(Predicted)

Sicherheit

Dimetacrine Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Isotonil,Siegfried,W. Germany,1967

Manufacturing Process

A mixture of 10.0 g of 5.5-dimethylacridan, 2.0 g of pulverized sodium amide and 6.5 g of 1-chloro-3-dimethylaminopropane in 50 ml of xylene is heated at reflux with stirring for one hour. To the cooled reaction mixture is added one volume of water. The organic layer is separated and extracted several times with diluted lactic acid. The acidic extracts are combined, washed with ether and neutralized by alkali. The crude 10-(3'-dimethylaminopropyl)-5,5- dimethylacridan is isolated by ether extraction and purified by distillation in a high vacuum. The yield is 6.4 g BP 170°-180°C/0.005mm. nD29 = 1.5990.
43 g of the base I are dissolved in 229 ml of 1 N aqueous d-tartaric acid and the clear solution so obtained is evaporated to dryness under reduced pressure. The residue is dissolved in 150 ml of 90% ethanol which solution after cooling gives the tartaric acid salt of I in white needles. The salt contains 1 mol of tartaric acid per 1 mol of the base. MP 155°-156°C. Easily soluble in cold water.

Therapeutic Function

Antidepressant

Dimetacrine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dimetacrine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 13)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd
+86-29-81139210 +86-18192627656
1059@dideu.com China 3003 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23541 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923
1026@dideu.com China 8670 58
TargetMol Chemicals Inc.
+8613564774135
zijue.cai@tsbiochem.com United States 19884 58
Chemwill Asia Co.,Ltd. 86-21-51086038
chemwill_asia@126.com CHINA 23912 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223;
psaitong@jm-bio.com China 29774 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58

  • Dimetacrine
  • dimethacrine
  • 9,10-Dihydro-9,9-dimethyl-10-(3-dimethylaminopropyl)acridine
  • 9,9-Dimethyl-10-[3-(dimethylamino)propyl]acridan
  • 3-(9,9-dimethylacridin-10-yl)-N,N-dimethyl-propan-1-amine
  • 3-(9,9-dimethylacridin-10-yl)-N,N-dimethylpropan-1-amine
  • 3-(9,9-dimethylacridin-10-yl)propyl-dimethyl-amine
  • 10(9H)-AcridinepropanaMine,N,N,9,9-tetraMethyl-
  • 4757-55-5
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