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ANTI-LAG-3

ANTI-LAG-3 Struktur
CAS-Nr.
Englisch Name:
ANTI-LAG-3
Synonyma:
ANTI-LAG-3;Anti-FDC protein;Anti-CD223 antigen;Anti-LAG3 antibody produced in rabbit;ANTI-LYMPHOCYTE ACTIVATION GENE-3 PROTEIN;Anti-Lymphocyte activation gene 3 protein precursor
CBNumber:
CB9104686
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-LAG-3 Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution

Sicherheit

ANTI-LAG-3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Allgemeine Beschreibung

The protein lymphocyte-activation gene 3 encoded by the gene LAG-3 is expressed by various lymphoid cell types and plasmacytoid dendritic cells.

Biochem/physiol Actions

The gene LAG3 (lymphocyte-activation gene 3) encodes a member of the Ig superfamily. The encoded protein is a CD4-related molecule that interacts with and binds to MHC class II. It functions in the regulation of plasmacytoid dendritic cell homeostasis. It is expressed by activated natural CD4+CD25+ Tregs (regulatory T cells) and enhances the suppressor activity of CD4+ T cells towards effector T cells. It is involved in the regulation of Treg homeostasis and function, apart from mediating induced Treg development. This immune inhibitory molecule also functions in mitigating dendritic cell differentiation and function. It functions in synergy with programmed cell death 1 (PD-1) to facilitate tumoral immune escape.

ANTI-LAG-3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-LAG-3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 8)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shanghai Hao Zhun Biological Technology Co., Ltd. --
info@zzsrm.com CHINA 6650 58
Beijing Bai Ao Si Biotechnology Co., Ltd. --
yangmei@bioneeds.net CHINA 6999 58
Shanghai Hao Biological Technology Co., Ltd. --
shxiyuanbio@163.com CHINA 6906 58
Beijing Taize Ruida Technology Co., Ltd. --
taizeorder@163.com CHINA 6536 58
Beijing Fubo Biotechnology Co., Ltd. --
info@f-biology.com CHINA 6025 58
Beijing Qiangxin Borui Biotechnology Co., Ltd. --
moumou@xxx.com CHINA 2992 58
Riedel-de Haen AG --
United States 6773 87
Vision BioSystems --
sales.usa@vision-bio.com United States 542 74

  • Anti-CD223 antigen
  • Anti-FDC protein
  • Anti-LAG3 antibody produced in rabbit
  • Anti-Lymphocyte activation gene 3 protein precursor
  • ANTI-LYMPHOCYTE ACTIVATION GENE-3 PROTEIN
  • ANTI-LAG-3
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