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L371,257

L371,257 Struktur
162042-44-6
CAS-Nr.
162042-44-6
Englisch Name:
L371,257
Synonyma:
257;L-371;L371,257;L371,257,L 371,257;1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one;1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine;2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-
CBNumber:
CB8850593
Summenformel:
C28H33N3O6
Molgewicht:
507.58
MOL-Datei:
162042-44-6.mol

L371,257 Eigenschaften

Siedepunkt:
728.9±60.0 °C(Predicted)
Dichte
1.282±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
L?slichkeit
Soluble to 10 mM in DMSO with gentle warming
Aggregatzustand
Powder
pka
0.73±0.20(Predicted)
Farbe
White to off-white

Sicherheit

L371,257 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

L-371,257 is a potent antagonist of oxytocin-induced contractions of the rat uterus in vitro and in vivo and has significant oral bioavailability in rats.

Biologische Aktivit?t

Potent, high affinity human oxytocin (OT) receptor antagonist (K i = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V 1a and V 2 . Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA 2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active.

L371,257 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

L371,257 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 32)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 4009686088
 3193328036@qq.com China 29764 68
Hebei Weite Medical Technology Co., Ltd 13180081292
 contact@wetogethermed.com China 7706 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581
 sales@chemhifuture.com China 3021 58
Shanghai Universal Biotech Co.,Ltd 13774214275
 zhouzz@univ-bio.com China 24996 58

162042-44-6()Verwandte Suche:

  • L371,257
  • 1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine
  • 1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
  • 2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-
  • 257
  • L-371
  • L371,257,L 371,257
  • 162042-44-6
  • C28H33N3O6
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