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3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Struktur
227619-65-0
CAS-Nr.
227619-65-0
Englisch Name:
3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
Synonyma:
HIP-B;(±)HIPB,(±) HIP B;3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID;rel-(3aR,6R,6aR)-Hexahydro-3-oxo-2H-pyrrolo[3,4-d]isoxazole-6-carboxylic acid;2H-Pyrrolo[3,4-d]isoxazole-6-carboxylic acid, hexahydro-3-oxo-, (3aR,6R,6aR)-rel-
CBNumber:
CB8839808
Summenformel:
C6H8N2O4
Molgewicht:
172.14
MOL-Datei:
227619-65-0.mol

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Eigenschaften

storage temp. 
Store at +4°C
Aggregatzustand
Powder
Wasserl?slichkeit
Soluble to 20 mM in water

Sicherheit

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

HIP-B is a potent, non-competitive excitatory amino acid transporter (EAAT) blocker. It can also be used as AMPA-Kainate receptor agonists.

Biologische Aktivit?t

Potent, non-competitive excitatory amino acid transporter (EAAT) blocker. Preferentially inhibits glutamate-induced [ 3 H]D-aspartate release (IC 50 = 1.2 μ M) rather than [ 3 H]L-glutamate uptake (IC 50 = 16.9 μ M). Moderately selective; displays no affinity for NMDA and metabotropic glutamate receptors, and low affinity for AMPA and kainate receptors (IC 50 values are 35 and 45 μ M respectively).

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 15)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Jinan ponder chemical co. LTD 0531-0000
thinklifescience@163.com China 19689 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8140 58
Energy Chemical 021-58432009 400-005-6266
 marketing@energy-chemical.com China 44918 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
United States Biological --
 sales@advtechind.com United States 6075 58
ApexBio Technology --
 sales@apexbt.com United States 6251 58
  • 3-HYDROXY-4,5,6,6A-TETRAHYDRO-3AH-PYRROLO[3,4-D]ISOXAZOLE-6-CARBOXYLIC ACID
  • HIP-B
  • 2H-Pyrrolo[3,4-d]isoxazole-6-carboxylic acid, hexahydro-3-oxo-, (3aR,6R,6aR)-rel-
  • rel-(3aR,6R,6aR)-Hexahydro-3-oxo-2H-pyrrolo[3,4-d]isoxazole-6-carboxylic acid
  • (±)HIPB,(±) HIP B
  • 227619-65-0
  • Glutamate receptor
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