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CARNOSOL

CARNOSOL Struktur
5957-80-2
CAS-Nr.
5957-80-2
Englisch Name:
CARNOSOL
Synonyma:
carnol;CARNOSOL;D-α-Alanine;Carnosol-RM;CARNOSOL(RG);CARNOSOL USP/EP/BP;Carnosol, 10 mM in DMSO;Carnosol(P)(Request Quote);Carnosol, froM RoseMarinus officinalis;Carnosol, 98%, from Rosemarinus officinalis
CBNumber:
CB8736565
Summenformel:
C20H26O4
Molgewicht:
330.42
MOL-Datei:
5957-80-2.mol

CARNOSOL Eigenschaften

Schmelzpunkt:
240～242℃
Siedepunkt:
524.8±50.0 °C(Predicted)
Dichte
1.26±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
L?slichkeit
DMSO:66.0(Max Conc. mg/mL);199.74(Max Conc. mM)
pka
8.91±0.40(Predicted)
Aggregatzustand
Solid
Farbe
White
Biologische Quelle
Rosemarinus officinalis L. leaves
LogP
2.832 (est)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
S-S?tze: 24/25
WGK Germany  3
HS Code  29322090
Giftige Stoffe Daten 5957-80-2(Hazardous Substances Data)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P302+P352 BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen.

CARNOSOL Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Carnosol is a phenol that has been found in rosemary (R. officinalis) and has diverse biological activities. It decreases nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at concentrations ranging from 6 to 25 μM. Carnosol scavenges peroxyl and hydroxyl radicals and inhibits lipid peroxidation in cell-free assays. It inhibits 5-lipoxygenase (5-LO; IC50 = 0.1 μM for the recombinant human enzyme) and the synthesis of leukotrienes in human polymorphonuclear leukocytes (PMNs; IC50 = 7 μM). In vivo, carnosol (200 mg/kg) reduces mammary DNA adduct formation and tumorigenesis in a rat model of DMBA-induced mammary tumorigenesis.

Chemische Eigenschaften

White powder

Verwenden

Carnosol is a phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, & anticarcinogen.

Cytotoxicity

IC50 (μg/mL): 65 (HL-60), 58 (K562), 50(Hep G2), 48 (MCF-7), 53 (MOLT-4)(Farimani et al. 2012)
IC50 (μg/mL): 61.46 (AGS) (Areche et al.2009)
IC50 (μg/mL): 2 (P388) (Aoyagi et al.2006)
IC50 (μg/mL): 1.19 (A2780), 3.30(SW1573), 8.59 (WiDr), 7.93 (T-47D),1.29 (HBL-100) (Guerrero et al. 2006).

CARNOSOL Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

EPIROSMANOL Rosmanol

CARNOSOL Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 215)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BINBO BIOLOGICAL CO.,LTD 		+8618629063126
 info@binbobiological.com China 447 58
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3619 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29863 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083
 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897
 sales@biopurify.com China 3772 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254
linda@hubeijusheng.com CHINA 28172 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19552 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39894 58
Shanghai Standard Technology Co., Ltd. 		18502101150
ft-sales@nature-standard.com CHINA 1923 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879
 sales@chemnorm.com CHINA 2935 58

5957-80-2()Verwandte Suche:

  • 1,3,4,9,10,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE
  • 1,3,4,9,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE
  • 1,2,3,4,4A,9,10,10AS-OCTAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISOPROPYL-9S, 4AR (EPOXYMETHANO)PHENANTHREN-12-ONE
  • CARNOSOL(RG)
  • CARNOSOL
  • Carnosol, froM RoseMarinus officinalis
  • Carnosol, 98%, from Rosemarinus officinalis
  • 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)-
  • CARNOSOL USP/EP/BP
  • (4aR,9S,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-2,3,4,9,10,10a-hexahydro-1H-9,4a-(epoxymethano)phenanthren-12-one
  • D-α-Alanine
  • carnol
  • (5b,7a)-11,12-Dihydroxy-7,20-epoxyabieta-8,11,13-trien-20-one
  • Carnosol(P)(Request Quote)
  • Carnosol-RM
  • Carnosol, 10 mM in DMSO
  • 5957-80-2
  • chemical reagent
  • pharmaceutical intermediate
  • Miscellaneous Natural Products
  • Antioxidant
  • Biochemicals Found in Plants
  • Nutrition Research
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
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