4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE
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- CAS-Nr.
- 749886-87-1
- Englisch Name:
- 4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE
- Synonyma:
- JSH-23;CS-1344;JSH-23 HCL;JSH-23;JSH23;JSH 23;NF-κB Activation Inhibitor II;NFκB Activation Inhibitor II, JSH-23;4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE;4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine;4-methyl-1-N-(3-phenylpropyl)benzene-1,2-diamine;JSH-23;JSH23;JSH 23;NF-ΚB ACTIVATION INHIBITOR II
- CBNumber:
- CB8649474
- Summenformel:
- C16H20N2
- Molgewicht:
- 240.34
- MOL-Datei:
- Mol file
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4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Eigenschaften
- Schmelzpunkt:
- 104.4-105.0℃
- Siedepunkt:
- 418.7±40.0 °C(Predicted)
- Dichte
- 1.086±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: >10mg/mL
- pka
- 5.99±0.11(Predicted)
- Aggregatzustand
- solid
- Farbe
- off-white to gray-pink
4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
A cell-permeable, selective blocker of nuclear translocation of NF-KB p65. NF-KB activation inhibitor II, JSH-23
Allgemeine Beschreibung
A cell-permeable diamino compound that selectively blocks nuclear translocation of NF-κB p65 and its transcription activity (IC
50 = 7.1 μM in a NF-κB reporter assay using RAW 264.7) without affecting IκB degradation. Shown to suppress DNA-binding of NF-κB and downregulate LPS-induced gene expression and apoptotic chromatin condensation.
Biochem/physiol Actions
Primary TargetBlocks nuclear translocation of NF-κB p65 and its transcription activity
4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 119)Lieferanten
749886-87-1()Verwandte Suche:
- 4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE
- JSH-23
- 4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine
- 4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine JSH 23
- JSH 23 4-Methyl-N1-(3-phenylpropyl)-1,2-benzenediamine
- 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine
- NFκB Activation Inhibitor II, JSH-23
- JSH-23;JSH23;JSH 23;NF-ΚB ACTIVATION INHIBITOR II
- NF-κB Activation Inhibitor II
- 4-methyl-1-N-(3-phenylpropyl)benzene-1,2-diamine
- JSH-23;JSH23;JSH 23
- CS-1344
- NF-κB Activation Inhibitor II, JSH-23 - CAS 749886-87-1 - Calbiochem
- 4-Methyl-N1-(3-phenylpropyl)-1,2-phenylenediamine>
- 1,2-Benzenediamine, 4-methyl-N1-(3-phenylpropyl)-
- 4-METHYL-N1-(3-PHENYLPROPYL)BENZENE-1,2-DIAMINE USP/EP/BP
- JSH-23 HCL
- Nuclear factor-κB,Nuclear factor-kappaB,JSH-23,NF-κB,JSH23,JSH 23,Inhibitor,inhibit
- JSH-23, 98%, an NF-κB inhibitor which inhibits NF-κB transcriptional activity
- JSH 23, NFkappaB transcriptional activity inhibitor
- 749886-87-1
- Chemical Amines
- Amines
- Aromatics
- Inhibitors
