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KETANSERIN TARTRATE

KETANSERIN TARTRATE Struktur
83846-83-7
CAS-Nr.
83846-83-7
Englisch Name:
KETANSERIN TARTRATE
Synonyma:
kjk-945;R 41468;R41468 tartrate;Ketanserin Tartrat;Ketanserinetartrate;KETANSERIN TARTRATE;R 41468 TARTRATE SALT;quinazoline-2,4(1H,3H);KETANSERIN TARTRATE SALT;3-(2-(4-(4-Fluorobenzoyl)
CBNumber:
CB8415888
Summenformel:
C26H28FN3O9
Molgewicht:
545.52
MOL-Datei:
83846-83-7.mol

KETANSERIN TARTRATE Eigenschaften

Schmelzpunkt:
183~186℃
storage temp. 
2-8°C
L?slichkeit
ethanol: 3.3mg/mL
Aggregatzustand
solid
Farbe
white
Wasserl?slichkeit
Soluble to 10 mM in water
CAS Datenbank
83846-83-7(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher T
R-S?tze: 25
S-S?tze: 22-36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS-Nr. VA1411195
HazardClass  6.1
HS Code  29335990
Toxizit?t LD50 oral in rat: 129mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung GHS hazard pictogramssrc="/GHS06.jpg" width="20" height="20" /> P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.

KETANSERIN TARTRATE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R25:Giftig beim Verschlucken.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Beschreibung

Ketanserin is a potent antagonist of the serotonin (5-HT) receptor that is selective for 5-HT2 (IC50 = 6.3 nM; Ki = 2.1 nM). It has no activity at 5-HT1 receptors but does have activity at histamine type 1, α1-adrenergic, and dopamine receptors with Ki values of 10, 10, and 220 nM, respectively. Ketanserin induces dose-dependent inhibition of contractile responses to 5-HT in isolated rat caudal artery, canine basilar, carotid, coronary and gastrosplenic arteries, and canine gastrosplenic and saphenous veins. Ketanserin (10 mg/kg/day) significantly decreases blood pressure (BP), blood pressure variability (BPV), and hypertensive organ damage in spontaneously hypertensive rats. Formulations containing ketanserin have been used to treat hypertension in early-onset preeclampsia.

Verwenden

coccidiostat

Biologische Aktivit?t

Selective 5-HT 2A serotonin receptor antagonist; can also be used to discriminate between 5-HT 1D and 5-HT 1B receptor subtypes.

KETANSERIN TARTRATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


KETANSERIN TARTRATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 137)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5978 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971
deasea125996@gmail.com China 2472 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998
sales@czwytech.com CHINA 904 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29811 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196
sale04@alfachem.cn China 13507 58
SIMAGCHEM CORP
+86-13806087780
sale@simagchem.com China 17365 58
Hebei Binshare New Material Co. Ltd
+8618633865755
china01@hbbinshare.com CHINA 955 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32080 58
Hebei Zhanyao Biotechnology Co. Ltd
15369953316 +8615369953316
admin@zhanyaobio.com China 2123 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15354 58

83846-83-7()Verwandte Suche:


  • R 41468
  • R 41468 TARTRATE SALT
  • 3-(2-(4-(p-fluorobenzoyl)-1-piperidinyl)ethyl)-2,4(1h,3h)-quinazolinedionel
  • 4(1h,3h)-quinazolinedione,3-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-(
  • kjk-945
  • r-(r*,r*))-2,3-dihydroxybutanedioate(1:1)
  • 3-[2-[4-(4-fluorobenzoyl)piperidino]ethyl]quinazoline-2,4(1H,3H)-dione [R-(R*,R*)]-tartrate
  • KETANSERIN TARTRATE (R 41468) (SELECTIVE 5-HT2/5-HT1C SEROTONI
  • Ketanserinetartrate
  • R 41468 (+)-tartrate salt, 3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt
  • 3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2,4-(1H,3H)-quinazolinedione tartrate
  • Ketanserin Tartrat
  • 3-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione 2,3-dihydroxysuccinate
  • 3-(2-(4-(4-Fluorobenzoyl)
  • -dione 2,3-dihydroxysuccinate
  • quinazoline-2,4(1H,3H)
  • Ketanserin tartrate salt Morpholino
  • 3-[2-(4-FLUOROBENZOYL)-1-PIPERDINYL]-ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE
  • 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERDINYL]ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE
  • 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERDINYL]ETHYL]-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE
  • 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,4[1H,3H]-QUINAZOLINEDIONE TARTRATE
  • 3-(2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL)-2,4(1H,3H)-QUINAZOLINEDIONE TARTRATE SALT
  • KETANSERIN TARTRATE
  • KETANSERIN TARTRATE SALT
  • R41468 tartrate
  • 3-[2-[4-[(4-fluorophenyl)-oxomethyl]-1-piperidin-1-iumyl]ethyl]-1H-quinazoline-2,4-dione
  • Ketanserin tartrate (R41468 tartrate)
  • Ketanserin Tartrate - CAS 83846-83-7 - Calbiochem
  • Ketanserin Hydrogen Tartrate
  • 2,4(1H,3H)-Quinazolinedione,3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-,(2R,3R)-2,3-dihydroxybutanedioate (1:1)
  • 3-(2-(4-(4-Fluorobenzoyl)piperidin-1-yl)ethyl)quinazoline-2,4(1H,3H)-dione (2R,3R)-2,3-dihydroxysuccinate
  • (.+-.)-TARTARIC ACID KETANSERIN HYDRATE
  • 83846-83-7
  • C22H22FN3O3C4H6O6
  • C26H28N3O9F
  • C4H6O6C22H22FN3O3
  • C26H28FN3O9
  • Biochemicals and Reagents
  • Enzyme Inhibitors
  • Other
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Type
  • BioChemical
  • Serotonin
  • Cardiovascular APIs
  • Serotonin receptor
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