(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
(R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity.
Biochem/physiol Actions
(R)-FTY720-OMe helps to block DNA synthesis and actin rearrangement induced by sphingosine 1-phosphate (S1P) in MCF-7 breast cancer cells. It can also reduce sphingosine kinase 2 (SK2) expression and prevent DNA synthesis in HEK 293 cells. (R)-FTY720-OMe has anti-breast cancer potential.
(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte