ANTI-PDI Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-Protein Disulfide Isomerase (DL-11) antibody produced in rabbit has been used in:
- immunofluorescence
- immunoprecipitation
- immunoblotting
Allgemeine Beschreibung
Protein Disulfide Isomerase is an abundant multifunctional, soluble enzyme (E.C. 5.3.4.1). PDI is expressed in cellular localizations such as the cell surface, cytosol and nucleus. PDI consists of four tandem domains, two of which contain a catalytic site for S-S bond formation. One domain is the main site of noncovalent interaction with other peptides or proteins. PDI has an N-terminal ER signal and C-terminal ER retention KDEL signal sequences.
Biochem/physiol Actions
Prolyl 4-hydroxylase subunit β (P4HB) acts as a molecular chaperone in the endoplasmic reticulum of cells and also as an oxidoreductase. It associates with steroid hormones and modulates their actions, concentrations and storage. P4HB accelerates the formation of disulphide bonds in proteins and hence aids in their folding.
ANTI-PDI Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
