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3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride

3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride Struktur
1393748-80-5
CAS-Nr.
1393748-80-5
Englisch Name:
3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride
Synonyma:
RY785;RY785, 10 mM in DMSO;Na+ channels,inhibit,RY785,Sodium Channel,RY-785,Na channels,RY 785,Inhibitor;Benzenepropanamide, 3-methoxy-α-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-;3-(3-methoxyphenyl)-2-methyl-N-[2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazol-5-yl]propanamide;3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride
CBNumber:
CB82678148
Summenformel:
C21H20N4O2S
Molgewicht:
392.47
MOL-Datei:
1393748-80-5.mol

3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride Eigenschaften

Dichte
1.333±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 15 mg/ml
Aggregatzustand
A crystalline solid
pka
9.81±0.10(Predicted)
Farbe
White to off-white

Sicherheit

3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

RY785 is a selective inhibitor of Kv2.1 voltage-gated potassium channels (IC50 = 0.05 μM) that does not affect Cav2 calcium channels. It displays over 100-fold selectivity for Kv2.1 over Cav1.2 (IC50 = 17 μM).

3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • 3-(3-Methoxyphenyl)-2-Methyl-N-(2-(thiazol-4-yl)-1H-benzo[d]iMidazol-5-yl)propanaMide hydrochloride
  • RY785
  • Benzenepropanamide, 3-methoxy-α-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-
  • Na+ channels,inhibit,RY785,Sodium Channel,RY-785,Na channels,RY 785,Inhibitor
  • 3-(3-methoxyphenyl)-2-methyl-N-[2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazol-5-yl]propanamide
  • RY785, 10 mM in DMSO
  • 1393748-80-5
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