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SB 290157 trifluoroacetate salt

SB 290157 trifluoroacetate salt Struktur
1140525-25-2
CAS-Nr.
1140525-25-2
Englisch Name:
SB 290157 trifluoroacetate salt
Synonyma:
SB290157 (trifluoroacetate);SB 290157 trifluoroacetate salt;SB290157 trifluoroacetate, 10 mM in DMSO;SB 290157 - CAS 1140525-25-2 - Calbiochem;SB 290157 TRIFLUOROACETATE; SB-290157 TRIFLUOROACETATE;N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine, 2,2,2-trifluor;N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine (trifluoroacetate);(2-(2,2-Diphenylethoxy)acetyl)-L-arginine 2,2,2-trifluoroacetate;(2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid;(2S)-5-(Diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoicacid,2,2,2-trifluoroaceticacid
CBNumber:
CB82537362
Summenformel:
C24H29F3N4O6
Molgewicht:
526.51
MOL-Datei:
1140525-25-2.mol

SB 290157 trifluoroacetate salt Eigenschaften

Schmelzpunkt:
>43°C (dec.)
storage temp. 
-20°C
L?slichkeit
Ethanol (Slightly, Sonicated), Methanol (Slightly), Water (Slightly)
Aggregatzustand
powder
Farbe
white to beige
Optische Aktivit?t
[α]/D +1.5 to +5°, c = 1.0 in DMSO
Stabilit?t:
Hygroscopic
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

SB 290157 trifluoroacetate salt Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SB 290157 Trifluoroacetate Salt is a selective, high affinity, competitive antagonist of anaphylatoxin C3a receptor.

Allgemeine Beschreibung

A non-peptide with anti-inflammatory properties that acts as a selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor (C3aR; IC50 = 200 nM). Does not antagonize C5aR or other chemotactic G-protein coupled receptors. Blocks C3a-induced internalization of C3aR in human neutrophils and C3a-induced Ca2+ mobilization in basophilic leukemia RBL-2H3 cells expressing murine, guinea pig, or human C3aR (IC50 = 7, 12.5, and 27.7 nM, respectively). Also blocks C3a-mediated ATP release from guinea pig platelets (IC50 = 30 nM).

Biochem/physiol Actions

Target IC50: 200 nM against the anaphylatoxin C3a receptor; 7, 12.5, and 27.7 nM, in blocking C3a-induced internalization of C3aR in human neutrophils and C3a-induced Ca2+ mobilization in basophilic leukemia RBL-2H3 cells expressing murine, guinea pig, or human C3aR

SB 290157 trifluoroacetate salt Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

SB 290157 trifluoroacetate salt Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 71)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034
 CHINA 3904 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501; +undefined18621343501
 product@acmec-e.com China 33338 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 		+8613817748580
 cooperation@kean-chem.com China 40066 58
Chembest Research Laboratories Limited +86-21-20908456
sales@BioChemBest.com China 6005 61
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
  • SB 290157 trifluoroacetate salt
  • SB290157 (trifluoroacetate)
  • SB 290157 TRIFLUOROACETATE; SB-290157 TRIFLUOROACETATE
  • SB 290157 - CAS 1140525-25-2 - Calbiochem
  • (2S)-5-(diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoic acid
  • N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine, 2,2,2-trifluor
  • N2-(2-(2,2-diphenylethoxy)acetyl)-L-arginine (trifluoroacetate)
  • SB290157,SB-290157 trifluoroacetate,Inhibitor,inhibit,SB 290157,Complement System,SB-290157,SB290157 trifluoroacetate
  • (2-(2,2-Diphenylethoxy)acetyl)-L-arginine 2,2,2-trifluoroacetate
  • (2S)-5-(Diaminomethylideneamino)-2-[[2-(2,2-diphenylethoxy)acetyl]amino]pentanoicacid,2,2,2-trifluoroaceticacid
  • SB290157 trifluoroacetate, 10 mM in DMSO
  • 1140525-25-2
  • C22H28N4O4CF3COOH
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