3-(2,2,2-Trimethylhydrazine)methylpropionate bromide
|
|
|
- CAS-Nr.
- 106966-25-0
- Englisch Name:
- 3-(2,2,2-Trimethylhydrazine)methylpropionate bromide
- Synonyma:
- Meldonium impurity C CRS;3-(2,2,2-Trimethylhydrazinyl)Methyl Propionate Bromide (Thmp);2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazin-1-ium Bromide;3-(2,2,2-Trimethylhydrazinyl)-propanoic acid methyl ester bromide;PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE;Hydrazinium, 2-(3-methoxy-3-oxopropyl)-1,1,1-trimethyl-, bromide (1:1)
- CBNumber:
- CB82464705
- Summenformel:
- C7H17N2O2.Br
- Molgewicht:
- 241.127
- MOL-Datei:
- 106966-25-0.mol
|
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide Eigenschaften
- Dichte
- 1.38 at 20℃
- Dampfdruck
- 5hPa at 20-25℃
- storage temp.
- 2-8°C
- LogP
- -3.26 at 24℃ and pH6.2
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
|
|
P273, P501 |
|
| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.
Synthese
In a three-necked round bottom flask equipped with a mechanical stirrer, a dropping funnel and a reflux condenser, 172 g (2 mol) of methyl acrylate was added, and under cooling, 132 g (2.2 mol) of 1,1-dimethylhydrazine was added dropwise. After a period of 2 hours, the reaction mixture was heated at the same temperature until methyl 3-(2,2-dimethylhydrazo)propionate was formed (monitored by GM-MS). The above methyl 3-(2,2-dimethylhydrazinyl)propanoate product was dissolved in 40% ethanol (350 ml), cooled to 0 ° C, and methyl bromide (189 g, 1.99 mol) was passed for 1 hour, and the temperature was continued. After stirring for 0, 5 hours, the yellow or brown precipitate was filtered off, and the crude product was washed with acetone (1000 ml). The crude 3-(2,2,2-trimethylhydrazine) propionate methyl bromide was dried (265.7 g, yield 91.0%); the crude product was recrystallized from ethanol and dried to give 219.8 g of pale yellow crystalline powder. The rate is 75.3%, the melting point is 130-132°C, and the main content is 103.3%. (The stability is verified by the stability test. The stability is poor, the color gradually becomes deeper. Because the trace impurities contained in the product have a great influence on the product, it is found to have molecular decay and various indicators. Larger, the product is valid for up to two years).
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-(2,2,2-Trimethylhydrazine)methylpropionate bromide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 26)Lieferanten
- PROPANOIC ACID, 3-(2,2,2-TRIMETHYLHYDRAZINYL)-, METHYL ESTER BROMIDE
- Meldonium impurity C CRS
- 3-(2,2,2-Trimethylhydrazinyl)-propanoic acid methyl ester bromide
- 2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazin-1-ium Bromide
- Hydrazinium, 2-(3-methoxy-3-oxopropyl)-1,1,1-trimethyl-, bromide (1:1)
- 3-(2,2,2-Trimethylhydrazinyl)Methyl Propionate Bromide (Thmp)
- 106966-25-0
- C7H17N2O2Br
