2,3-dimethyl-6-nitro-2H-indazole
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- CAS-Nr.
- 444731-73-1
- Englisch Name:
- 2,3-dimethyl-6-nitro-2H-indazole
- Synonyma:
- Pazopanil impurity 11;Pazopanib Impurity 19;3-Methly-6-nitroindazole;2,3-dimethyl-6-nitrobazole;2,3-Dimethyl-6-nitro-1H-i...;2,3-dimethyl-6-nitro-indazole;3-diMethyl-6-nitro-2H-indazole;2,3-dimethyl-6-nitro-1H-indazole;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE;2H-Indazole, 2,3-diMethyl-6-nitro-
- CBNumber:
- CB82455022
- Summenformel:
- C9H9N3O2
- Molgewicht:
- 191.19
- MOL-Datei:
- 444731-73-1.mol
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2,3-dimethyl-6-nitro-2H-indazole Eigenschaften
- Schmelzpunkt:
- 183-186°C
- Siedepunkt:
- 377.0±22.0 °C(Predicted)
- Dichte
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- -0.55±0.30(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Yellow
Sicherheit
2,3-dimethyl-6-nitro-2H-indazole Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
2,3-Dimethyl-6-nitro-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
structure and hydrogen bonding
In the mol-ecule of 2,3-dimethyl-6-nitro-2H-indazole, C9H9N3O2, the indazole ring system is almost planar [maximum deviation = 0.019 (3) Å for the C atom bearing the nitro group]. In the crystal structure, inter-molecular C—H...O inter-actions link the mol-ecules into centrosymmetric dimers, forming R 2 2(18) ring motifs. Aromatic π–π contacts between indazole rings [centroid–centroid distances = 3.632 (1) and 3.705 (1)?] may further stabilize the structure[1].
2,3-dimethyl-6-nitro-2H-indazole Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2,3-dimethyl-6-nitro-2H-indazole Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 199)Lieferanten
444731-73-1()Verwandte Suche:
- 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE
- 2,3-dimethyl-6-nitro-1H-indazole
- 2,3-Dimethyl-6-nitro-1H-i...
- 2H-Indazole, 2,3-diMethyl-6-nitro-
- 3-Methly-6-nitroindazole
- 3-diMethyl-6-nitro-2H-indazole
- Pazopanib Impurity 19
- 2,3-dimethyl-6-nitro-indazole
- 2,3-dimethyl-6-nitrobazole
- 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001：2015 REACH
- Pazopanil impurity 11
- 444731-73-1
