(16α,19E)-1-Acetyl-19,20-didehydrocuran-17-ol Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
This alkaloid has been isolated from Strychnos holstii var. reticulata f. condensata
and may be purified by recrystallization from AcOEt or heptane when it yields
clusters of colourless needles. It is dextrorotatory with [α]
D + 23° (c 0.7,
MeOH) and gives an ultraviolet spectrum which exhibits a single absorption
maximum at 254.4 mIJ.. It is only sparingly soluble in heptane or Et20, more so
in C6H6 and freely soluble in MeOH, EtOH, Me2CO or CHC13. The alkaloid has
been synthesized via the lactam produced from strychnine or the WielandGumlich aldehyde.
Einzelnachweise
Bosley.,J. Pharrn. Belg., 6,150,243 (1951)
Structure:
Bisset., Chern. Ind., 1036 (1965)
Synthesis:
Wenkert, Sklar.,J. Org. Chern., 31,2689 (1966)
Hymon, Schmid., Helv. Chirn. Acta., 49,2067 (1966)
(16α,19E)-1-Acetyl-19,20-didehydrocuran-17-ol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte