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napyradiomycin A1

napyradiomycin A1 Struktur
103106-24-7
CAS-Nr.
103106-24-7
Englisch Name:
napyradiomycin A1
Synonyma:
WS-9558A;Napyradiomycin A;napyradiomycin A1;3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione;2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-
CBNumber:
CB81373343
Summenformel:
C25H30Cl2O5
Molgewicht:
481.413
MOL-Datei:
103106-24-7.mol

napyradiomycin A1 Eigenschaften

Siedepunkt:
642.5±55.0 °C(Predicted)
Dichte
1.31±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
Aggregatzustand
A solid
pka
6.14±0.70(Predicted)

Sicherheit

HS Code  29419000
Toxizit?t mouse,LD50,intraperitoneal,> 250mg/kg (250mg/kg),Journal of Antibiotics. Vol. 39, Pg. 487, 1986.

napyradiomycin A1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Napyradiomycin A1 is a fungal metabolite originally isolated from C. rubra and has diverse biological activities. It is active against S. aureus, M. luteus, B. anthracis, C. bovis, and M. smegmatis (MICs = 1.56-12.5 μg/ml). Napyradiomycin A1 is an estrogen receptor antagonist (IC50 = 4.2 μM in rat uterine homogenates). It also inhibits mitochondrial NADH:ubiquinone oxidoreductase (complex I) and succinate:ubiquinone oxidoreductase (complex II) activities in bovine heart homogenates (IC50s = 20 and 9.7 μM, respectively).

Verwenden

Napyradiomycin derivatives have antibacterial and tumor properties. Napyradiomycin A1 is a secondary metabolite isolated from Streptomyces. It is also an antibacterial antibiotic and an inhibitor of mitochondrial complexes I and II.

napyradiomycin A1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

napyradiomycin A1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 12)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 14055 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Zhejiang Huida Biotech Co., LTD 0571-89903882 13626641628
 jiangnan@huidabiotech.com China 3656 58
Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
3477467573@qq.com China 8617 58
Zhejiang Huida Biotech Co., LTD 0571-0571-89903882 15990081639
 sunshixuan@huidabiotech.com China 3705 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11974 58
Guangzhou Yaoguang Technology Co., Ltd. 13020159086
 yangjue@ygfuture.com China 622 58

103106-24-7()Verwandte Suche:

  • napyradiomycin A1
  • 3,4a-Dichloro-6,8-dihydroxy-3,4,4a,10a-tetrahydro-2,2-dimethyl-10a-(3,7-dimethyl-2,6-octadienyl)-2H-naphtho[2,3-b]pyran-5,10-dione
  • Napyradiomycin A
  • WS-9558A
  • 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-10a-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3,4,4a,10a-tetrahydro-6,8-dihydroxy-2,2-dimethyl-, (3R,4aR,10aS)-
  • 103106-24-7
  • C25H30Cl2O5
  • Antibiotic
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