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Enclomiphene

Enclomiphene Struktur
15690-57-0
CAS-Nr.
15690-57-0
Englisch Name:
Enclomiphene
Synonyma:
enclomiphene;Enclomifene;EncloMiphene-d4;trans-2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-n,n-diethylethanamine;ici46476;RMI 16,289;(E)-Clomiphene;trans-clomifene;E-CloMiphene-d4;trans-clomiphene
CBNumber:
CB8128416
Summenformel:
C26H28ClNO
Molgewicht:
405.96
MOL-Datei:
15690-57-0.mol

Enclomiphene Eigenschaften

Schmelzpunkt:
149.0-150.5°
Siedepunkt:
509.0±50.0 °C(Predicted)
Dichte
1.104±0.06 g/cm3(Predicted)
pka
9.60±0.25(Predicted)
InChI
InChI=1S/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25+
InChIKey
GKIRPKYJQBWNGO-OCEACIFDSA-N
SMILES
C(N(CC)CC)COC1=CC=C(/C(/C2=CC=CC=C2)=C(/Cl)\C2=CC=CC=C2)C=C1

Sicherheit

Enclomiphene Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Enclomiphene is a synthetic and nonsteroidal antiestrogen. It is the more potent isomer and the one responsible for its ovulation-inducing actions. The half-life of enclomiphene is relatively short, so serum concentrations rise and fall quickly during and after treatment. Antiestrogens represent the first-line treatment strategy in WHO class-2 anovulatory infertility.

Verwenden

trans-Clomiphene is a Clomiphene (C587025) stereoisomer, a synthetic estrogen agonist-antagonist. Gonad-stimulating principle. Treatment for infertility.

synthetische

CONDENSATION OF 4-HYDROXYBENZOPHENONE WITH 2-(DIETHYLAMINO)ETHYL CHLORIDE FOLLOWED BY TREATMENT WITH BENZYL MAGNESIUM CHLORIDE AND DEHYDRATION TO GIVE 2-(P-(1,2-DIPHENYLVINYL)PHENOXY)TRIETHYLAMINE WHICH IS CHLORINATED AND TREATED WITH CITRIC ACID /CITRATE/

Biologische Aktivit?t

Enclomiphene is the trans-isomer of clomiphene citrate (CC). It has a higher rate of clearance and is less active than the cis-isomer, cis-clomiphene. Clomiphene citrate has been evaluated for antineoplastic activity against breast cancer.

Mode of action

Enclomiphene is a non-steroidal estrogen receptor antagonist that promotes gonadotropin-dependent testosterone secretion by the testes. The main mechanism of its action is thought to be its antagonistic effects on the hypothalamic-pituitary axis and stimulation of GnRH secretion.

Enclomiphene Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Enclomiphene Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 53)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Xianhe Biotech Co., Ltd
+8617709210191
Jerry@xhobio.com China 882 58
Shandong Huisheng Import & Export Co., Ltd.
+86-13176845580 +86-13176845580
da@zhongda-biotech.com China 232 58
Anhui Zhongda Biotechnology Co., Ltd
+8615689548120
linda@zhongda-biotech.com China 193 58
Hebei Xinsheng New Material Technology Co., LTD.
+86-16632316109
xinshengkeji@xsmaterial.com China 1085 58
Anhui Ruihan Technology Co., Ltd
+8617756083858
daisy@anhuiruihan.com China 973 58
American HealthyMorph LLC
+8613363867578
13363867578@163.com China 101 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23541 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Nanjing Doge Biomedical Technology Co., Ltd
+86-25-58227606 +86-15305155328
sales@dogechemical.com China 4128 58

15690-57-0()Verwandte Suche:


  • 2-diphenylethenyl)phenoxy)-n,n-diethyl-2-(4-(2-chloro-(e)-ethanamin
  • 2-diphenylvinyl)phenoxy)-2-(p-(2-chloro-(e)-triethylamin
  • ici46476
  • trans-2-(p-(2-chloro-1,2-diphenylvinyl)phenoxy)triethylamine
  • trans-clomifene
  • trans-clomiphene
  • TRANS-CLOMIPHENE HCL
  • RMI 16,289
  • E-CloMiphene-d4
  • Cis-cloMiphene (ZucloMiphene)
  • Ethanamine, 2-[4-[(1E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethyl-
  • (E)-Clomiphene
  • Enclomifene
  • EncloMiphene-d4
  • trans-2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-n,n-diethylethanamine
  • enclomiphene
  • Androxal(Enclomiphene) 25mg Tablets
  • 15690-57-0
  • 15690-57-0
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