ANTI-BAP1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit .

Allgemeine Beschreibung

RING finger protein 2 (RNF2), also known as RNF1b, consists of 336 amino acids and it belongs to PcG (polycomb-group) protein family. This protein is encoded by the gene mapped on human chromosome 1q25.3. The encoded protein is characterized with a unique C3HC4 RING finger motif.

Biochem/physiol Actions

RING finger protein 2 (RNF2), in association with prohibitin, regulates the activity of E2F transcription factor 1(E2F1) by the direct, prohibitin-mediated pathway and the indirect, p16-mediated pathway. Rnf2 might act as a vital assembly factor in PRC (Polycomb repressive complex), which is required for mammalian development. Decrease in the expression of Rnf2 or ring1b causes gastrulation arrest and cell cycle inhibition. Overexpression of RNF2 results in pathogenesis of urothelial carcinoma of the bladder (UCB). RNF2 interacts with E2 ubiquitin-conjugating enzymes and display E3 ubiquitin ligase activity. RNF2 plays a crucial role in cancer cell survival and proliferation, therefore it can serve as a potential therapeutic target for cancer treatment and prevention.

ANTI-BAP1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ANTI-BAP1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Yubo Biotechnology Co., Ltd.	--	shybio@126.com	CHINA	6967	58
Beijing Bi Orange Blue Biotechnology Co., Ltd.	--	bo49855987@163.com	CHINA	6827	58
Shanghai Hao Biological Technology Co., Ltd.	--	market@xlswkj.com	CHINA	6793	58
Shanghai Beinuo Biotechnology Co., Ltd.	--	beinuobio@163.com	CHINA	6580	58
Beijing Bai Ao Si Biotechnology Co., Ltd.	--	yangmei@bioneeds.net	CHINA	6999	58
Shanghai Zeye Biotechnology Co., Ltd.	--	shzeysw@163.com	CHINA	6549	58
Beijing Dongge Boye Biotechnology Co., Ltd.	--	1861586486@qq.com	CHINA	6648	58
Suzhou Ruinuode Biotechnology Co., Ltd.	--	2090855807@qq.com	CHINA	6063	58
Beijing Luyuan Bird Biotechnology Co., Ltd.	--	15810802415@139.com	CHINA	6750	58
Beijing Zhijie Fangyuan Technology Co., Ltd.	--	15810200961@163.com	CHINA	6984	58

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• ANTI-BAP1
• ANTI-BRCA1 ASSOCIATED PROTEIN 1
• Monoclonal Anti-BAP1 antibody produced in mouse
• Anti-DING
• Anti-Ring finger protein 2
• Anti-RNF2/DING antibody produced in goat
• Monoclonal Anti-MAGI1 antibody produced in mouse
• Anti-RNF2 (AB2) antibody produced in rabbit
• Anti-RNF2 (1-15) antibody produced in rabbit
• Anti-AIP3
• Anti-BAIAP1
• Anti-membrane associated guanylate kinase, WW and PDZ domain containing 1
• Anti-TNRC19
• Anti-WWP3
• Anti-HIPI3
• Anti-RING1B
• Monoclonal Anti-RNF2 antibody produced in mouse
• Anti-RNF2 (AB1) antibody produced in rabbit
• Anti-RNF2 antibody produced in rabbit
• Anti-BAP1 antibody produced in rabbit
• Anti-BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
• Anti-hucep-6
• Anti-KIAA0272
• Anti-UCHL2