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6,6'-Dihydroxy-3,3'-diarsen-1,2-diyldianiliniumdichlorid

Arsphenamine Struktur
139-93-5
CAS-Nr.
139-93-5
Bezeichnung:
6,6'-Dihydroxy-3,3'-diarsen-1,2-diyldianiliniumdichlorid
Englisch Name:
Arsphenamine
Synonyma:
SALVARSAN;arsphenamine;3,3'-Diamino-4,4'-Dihydroxyarsenobenzene;4,4-ARSENOBIS(2-AMINOPHENOL)DIHYDROCHLORIDE;6,6'-dihydroxy-3,3'-diarsene-1,2-diyldianilinium dichloride;2-amino-4-(3-amino-4-hydroxyphenyl)arsanylidenearsanylphenol
CBNumber:
CB7933479
Summenformel:
C12H14As2Cl2N2O2
Molgewicht:
439.00096
MOL-Datei:
139-93-5.mol

6,6'-Dihydroxy-3,3'-diarsen-1,2-diyldianiliniumdichlorid Eigenschaften

Schmelzpunkt:
190°C (rough estimate)
Aggregatzustand
solid

Sicherheit

Toxizit?t LD100 i.v. in rats: 140 mg/kg (Schamberg)

6,6'-Dihydroxy-3,3'-diarsen-1,2-diyldianiliniumdichlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

Pharmazeutische Anwendungen

Salvarsan was a synthetic arsenic-based drug discovered in 1909 by Ehrlich and his team. In 1910, Ehrlich introduced Salvarsan (3-amino-4-hydroxyphenylarsenic), also known as arsphenamine or compound 606, to the market as a cure for syphilis caused by the bacterium Treponema pallidum.
Eventually, compound 606 was synthesised and introduced as an agent against syphilis. The compound was later marketed as Salvarsan, receiving its name from the Latin word salvare , which means to preserve, to heal. In 1909 and 1910, the first human tests on patients with syphilis and relapsing fever were extremely successful, and Salvarsan was marketed from 1910. For the first time, an infectious and fatal disease in humans could be treated with a man-made molecule, and Salvarsan brought Ehrlich world-wide fame. Generally, the use of arsenic-based drugs has ceased, especially as a result of the development of Penicillin. Nevertheless, Melarsoprol and an arsenic-based drug closely related to Atoxyl are licensed to treat sleeping sickness.

6,6'-Dihydroxy-3,3'-diarsen-1,2-diyldianiliniumdichlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


6,6'-Dihydroxy-3,3'-diarsen-1,2-diyldianiliniumdichlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 4)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Portail Substances Chimiques --
webmestre-substances@ineris.fr France 6024 58
Molekula Ltd --
info@molekula.com United Kingdom 4060 50
HONEST JOY HOLDINGS LIMITED --
sales@honestjoy.cn United States 6675 54
Yick-Vic Chemicals & Pharmaceuticals (HK) Ltd --
sales@yickvic.com China 6206 58

  • 6,6'-dihydroxy-3,3'-diarsene-1,2-diyldianilinium dichloride
  • 3,3'-Diamino-4,4'-Dihydroxyarsenobenzene
  • 4,4-ARSENOBIS(2-AMINOPHENOL)DIHYDROCHLORIDE
  • SALVARSAN
  • arsphenamine
  • 2-amino-4-(3-amino-4-hydroxyphenyl)arsanylidenearsanylphenol
  • 139-93-5
  • C12H12As2N2O22HCl
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