2-Cyanacetamid
|
|
|
- CAS-Nr.
- 107-91-5
- Bezeichnung:
- 2-Cyanacetamid
- Englisch Name:
- 2-Cyanoacetamide
- Synonyma:
- CYANOACETAMIDE;ACETAMIDE, 2-CYANO-;Cyanacetamide;Kyanacetamid;CYANOACETIC AMIDE;CYAC;2-CAA;usafkf-14;USAF kf-14;Cyanacetamid
- CBNumber:
- CB7852727
- Summenformel:
- C3H4N2O
- Molgewicht:
- 84.08
- MOL-Datei:
- 107-91-5.mol
|
2-Cyanacetamid Eigenschaften
- Schmelzpunkt:
- 119-121 °C(lit.)
- Siedepunkt:
- 154.34°C (rough estimate)
- Dichte
- 1,4 g/cm3
- Brechungsindex
- 1.5110 (estimate)
- Flammpunkt:
- 419 °F
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- cold water: soluble1gm in 6.5ml
- Aggregatzustand
- Crystalline Powder
- pka
- -1.27±0.10(Predicted)
- Farbe
- White to light cream
- Geruch (Odor)
- Odorless
- Wasserl?slichkeit
- soluble
- Merck
- 14,2688
- BRN
- 878221
- CAS Datenbank
- 107-91-5(CAS DataBase Reference)
- NIST chemische Informationen
- Acetamide, 2-cyano-(107-91-5)
- EPA chemische Informationen
- 2-Cyanoacetamide (107-91-5)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
2-Cyanacetamid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
White or light yellow needle crystal or powder. Slightly soluble in water, easily soluble in ethanol.
Verwenden
2-Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence and is useful for the automated analysis of carbohydrates as borate complexes. It can also be used in the synthesis of heterocyclic compounds such as pyrazole, pyridine and pyrimidine derivatives. Moreover, it can also be applied for the spectrophotometric assay of the enzyme activity of cellulose in related host cells.
synthetische
Cyanoacetamide can be prepared from ethyl cyanoacetate and ammonia. Cool the ethyl cyanoacetate to below 200°C, add concentrated ammonia water to react, and the mixture turns from turbid to clear. After cooling in cold water for 20 minutes, a precipitate is precipitated. After filtration and drying, the crude product is obtained, and then the crude product of cyanoacetamide is added. In the boiling ethanol, after dissolving it, add a small amount of activated carbon for decolorization and purification, filter, cool the filtrate to separate out the precipitate, and dry it at 80-100 ℃ to obtain the fine cyanoacetamide.
Definition
2-Cyanoacetamide is an acetic amide with a nitrile functional group. It is a codon of glutamine that directs the placement of glutamine into a polypeptide.
Allgemeine Beschreibung
Cyanoacetamide is the starting reagent for vitamin B
6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.
l?uterung methode
Crystallise the amide from MeOH/dioxane (6:4), then water and dry it over P2O5 under vacuum. [Beilstein 2 IV 1891.]
2-Cyanacetamid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Disperse Yellow H-4GL
Allopurinol
METHYL 3-AMINO-6-METHYLTHIOPHENO[2,3-B]PYRIDINE-2-CARBOXYLATE
Buspiron
2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINIC ACID
2-Chloro-6-methyl-3-pyridinecarbonitrile
2-Chloro-6-methylpyridine-4-carboxylic acid
3-AMINO-6-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-amine
Malons?uredinitril
5-BROMO-2-CHLORO-4,6-DIMETHYLNICOTINONITRILE
Olprinone
1,4,6-Trimethyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine ,97%
2,4-Dicyan-3-methylglutaramid
2-CHLORO-6-METHYLPYRIDINE-4-CARBONYL CHLORIDE
ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE
2-AMINO-5-PHENYL-3-THIOPHENECARBOXAMIDE
Pyrimidin-2,4,6-triyltriamin
2-AMINO-6-METHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
2,6-DICHLORO-3-HYDROXYPYRIDINE-4-CARBOXYLIC ACID
2-Hydroxy-4,6-dimethylnicotinonitril
Entacapone
3-aminopropanamide
4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3-D][1,2,3]TRIAZINE-5-CARBOXAMIDE
2,2-Dibrom-2-cyanacetamid
1,2-Dihydro-6-methyl-2-oxonicotinonitril
2-Chloro-3-cyano-4,6-dimethylpyridine
2-Methylisonicotinic acid
5-BROMO-4,6-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE
Milrinon
4-AMINOPYRIMIDINE-5-CARBOXAMIDE
4,6-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE
2-Cyan-2-[2,3-dihydro-3-(tetrahydro-2,4,6-trioxo-5(2H)-pyrimidinyliden)-1H-isoindol-1-yliden]-N-methylacetamid
2-Cyanacetamid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 657)Lieferanten
107-91-5(2-Cyanacetamid)Verwandte Suche:
- amidkyselinykyanoctove
- cyanoiminoaceticacid
- Malonamide nitrile
- malonamidenitrile
- Malonamonitrile
- monoamidemononitrile-malonicaci
- Nitrilomalonamide
- Propionamide, 3-nitrilo-
- propionamidenitrile
- USAF kf-14
- usafkf-14
- ALPHA-CYANOACETAMIDE
- a-L-Chloropropionic acid
- Amid kyseliny kyanoctove (czech)
- 3-Oxo-3-aminopropiononitrile
- Carbamoylacetonitrile
- 2-Cyanoacetamide,99%
- CYANOACETAMIDE FOR SYNTHESIS 250 G
- CYANOACETAMIDE FOR SYNTHESIS 1 KG
- 2-CyanoacetaMide, 99% 100GR
- CyanoacetaMide (CAA)
- CyanoacetaMide 99%
- CyanoacetaMide, 95+%
- Cyanide acetaMide
- 2-cyano-acetamid
- 2-cyanoethanamide
- LABOTEST-BB LT01406239
- MALONAMIDONITRILE
- CYAC
- Cyanacetamid
- 3-Nitrilo-propionamide
- Amid kyseliny kyanoctove
- 2-CAA
- 2-CYANOACETAMIDE
- 2-Cyanacetamid
- Milrinone Impurity T
- 2-Cyanoacetamide (CAA)
- 2-Cyanoacetamide >
- 2-Cyanoacetamide ISO 9001：2015 REACH
- Test Sample Is Free----2-Cyanoacetamide (CAA) CAS 107-91-5
- Kyanacetamid
- ACETAMIDE, 2-CYANO-
- CYANOACETAMIDE
- CYANOACETIC AMIDE
- Cyanacetamide
- Cyanoacetamide 98% For Synthesis
- 107-91-5
- NCCH2CONH2
- Carbonyl Compounds
- Building Blocks
- Amides
- Organic Building Blocks
- used as medicine, dye and plating solution intermediates
- fine chemicals
- amine series
- Agrochemicals
- Carbonyl Compounds
- Fluorescence
