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15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)- Struktur
135635-50-6
CAS-Nr.
135635-50-6
Englisch Name:
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-
Synonyma:
Deshydroxy Tarcolimus;Tacrolimus Impurity 34;(S)-1-(2-((2R,3R,5S,6R)-6-((1S,3S,5Z,7R,9E,11R,12S,13E)-7-allyl-12-hydroxy-14-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methoxy-3,5,11,13-tetramethyl-8-oxotetradeca-5,9,13-trien-1-yl)-2-hydroxy-5-;15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-;(S)-1-(2-((2R,3R,5S,6R)-6-((1S,3S,5Z,7R,9E,11R,12S,13E)-7-allyl-12-hydroxy-14-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methoxy-3,5,11,13-tetramethyl-8-oxotetradeca-5,9,13-trien-1-yl)-2-hydroxy-5-methoxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid
CBNumber:
CB78371312
Summenformel:
C44H69NO11
Molgewicht:
788.02
MOL-Datei:
135635-50-6.mol

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)- Eigenschaften

Siedepunkt:
848.5±75.0 °C(Predicted)
Dichte
1.16±0.1 g/cm3(Predicted)
pka
9.97±0.70(Predicted)

Sicherheit

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Deshydroxy Tarcolimus is an impurity of Tacrolimus(F370000). Tacrolimus is an immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 4)Lieferanten
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ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396
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ShenZhen H&D Pharmaceutical Technology Co., LTD 13986652530
 2851922763@qq.com China 7957 58
Nantong Hanfang Biotechnology Co. , Ltd. hanfangpharma@126.com; 18616537568
 hanfangpharma@126.com China 29981 58
  • 15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-19-hydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-
  • Deshydroxy Tarcolimus
  • Tacrolimus Impurity 34
  • (S)-1-(2-((2R,3R,5S,6R)-6-((1S,3S,5Z,7R,9E,11R,12S,13E)-7-allyl-12-hydroxy-14-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methoxy-3,5,11,13-tetramethyl-8-oxotetradeca-5,9,13-trien-1-yl)-2-hydroxy-5-
  • (S)-1-(2-((2R,3R,5S,6R)-6-((1S,3S,5Z,7R,9E,11R,12S,13E)-7-allyl-12-hydroxy-14-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methoxy-3,5,11,13-tetramethyl-8-oxotetradeca-5,9,13-trien-1-yl)-2-hydroxy-5-methoxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylic acid
  • 135635-50-6
  • C44H69NO11
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