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Dolutegravir O-β-D-Glucoside

Dolutegravir O-β-D-Glucoside Struktur
1822365-49-0
CAS-Nr.
1822365-49-0
Englisch Name:
Dolutegravir O-β-D-Glucoside
Synonyma:
Unii-29LH9led64;Dolutegravir O-β-D-Glucoside;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-(β-D-glucopyranosyloxy)-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
CBNumber:
CB76044867
Summenformel:
C26H29F2N3O10
Molgewicht:
581.53
MOL-Datei:
1822365-49-0.mol

Dolutegravir O-β-D-Glucoside Eigenschaften

Schmelzpunkt:
>136°C (dec.)
Siedepunkt:
891.2±65.0 °C(Predicted)
Dichte
1.62±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
10.63±0.40(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White

Sicherheit

Dolutegravir O-β-D-Glucoside Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Dolutegravir O-β-D-Glucoside is a metabolite of Dolutegravir (D528800); a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir O-β-D-Glucoside Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Dolutegravir O-β-D-Glucoside Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 2)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
guoyungurui 18162595016; 18162595016
3287908757@qq.com China 10335 58

  • Dolutegravir O-β-D-Glucoside
  • 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2,4-difluorophenyl)methyl]-7-(β-D-glucopyranosyloxy)-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-, (4R,12aS)-
  • Unii-29LH9led64
  • 1822365-49-0
  • C26H29F2N3O10
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