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MMP-3 INHIBITOR VIII

MMP-3 INHIBITOR VIII Struktur
208663-26-7
CAS-Nr.
208663-26-7
Englisch Name:
MMP-3 INHIBITOR VIII
Synonyma:
MMP3 inhibitor 2;MMP-3 INHIBITOR VIII;2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide;N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE;Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-
CBNumber:
CB7481925
Summenformel:
C20H26N2O5S
Molgewicht:
406.5
MOL-Datei:
Mol file

MMP-3 INHIBITOR VIII Eigenschaften

Dichte
1.245±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
Aggregatzustand
A crystalline solid
pka
9.13±0.40(Predicted)

Sicherheit

MMP-3 INHIBITOR VIII Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Matrix metalloproteinases (MMPs) belong to a family of proteases that play a crucial role in tissue remodeling and repair by degrading extracellular matrix proteins to enable cell migration. MMP-3 (also known as stromelysin-1) is thought to play a role in the vascular remodeling that occurs during aneurysm formation and may also be involved in wound repair, progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII is a cell permeable sulfonamide-based hydroxamic acid that binds to the active site of MMP-3 (Ki = 23 nM) and prevents its activity. This compound has also been shown to inhibit mouse macrophage metalloelastase MME/MMP-12 with an IC50 value of 13 nM.

MMP-3 INHIBITOR VIII Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

MMP-3 INHIBITOR VIII Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Aladdin Scientific 		+1-+1(833)-552-7181
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VDM Biochemicals 0330-2528181
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BOC Sciences 1-631-485-4226; 16314854226
 info@bocsci.com United States 14055 65
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11217 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8140 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195
 sales@tybiochem.com China 6813 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11974 58
TargetMol Chemicals Inc. 15002134094
 marketing@targetmol.cn China 19711 58
  • MMP-3 INHIBITOR VIII
  • N-HYDROXY-2(R)-[[(4-METHOXYPHENYL)SULFONYL]-[BENZYLAMINO]-4-METHYLPENTANAMIDE
  • 2-[benzyl-(4-methoxyphenyl)sulfonylamino]-N-hydroxy-4-methylpentanamide
  • Pentanamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](phenylmethyl)amino]-4-methyl-
  • MMP3 inhibitor 2
  • 208663-26-7
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