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Lup-20(29)-en-28-olsure, 3-Hydroxy-, Methylester, (3β)-

BETULINIC ACID METHYL ESTER Struktur
2259-06-5
CAS-Nr.
2259-06-5
Bezeichnung:
Lup-20(29)-en-28-olsure, 3-Hydroxy-, Methylester, (3β)-
Englisch Name:
BETULINIC ACID METHYL ESTER
Synonyma:
Methylbetulinate;betulinate, Methyl;BETULINIC ACID METHYL ESTER;BETULINIC ACID METHYL ESTER hplc;BETULINIC ACID METHYLESTER WITH HPLC;3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)-;Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)-
CBNumber:
CB7322703
Summenformel:
C31H50O3
Molgewicht:
470.73
MOL-Datei:
2259-06-5.mol

Lup-20(29)-en-28-olsure, 3-Hydroxy-, Methylester, (3β)- Eigenschaften

Schmelzpunkt:
222-223°C
Siedepunkt:
523.5±33.0 °C(Predicted)
Dichte
1.036±0.06 g/cm3(Predicted)
pka
15.16±0.70(Predicted)
Aggregatzustand
A solid
LogP
9.400 (est)

Sicherheit

Lup-20(29)-en-28-olsure, 3-Hydroxy-, Methylester, (3β)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Betulinic acid methyl ester is a lupane-type triterpenoid and an esterified version of betulinic acid that has been found in Helicteres hirsuta and has diverse biological activities. It inhibits HIV-1 reverse transcriptase (IC50 = 11 μM). Betulinic acid methyl ester is active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively). It induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM). Betulinic acid methyl ester is cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively).

Biologische Aktivit?t

Betulinic acid methyl ester is a natural compound extracted from the bark of the birch tree with anti-inflammatory and antiprotozoal activity.  Studies have shown it to be a potent inhibitor of cancer cell growth in vitro and in vivo.  It has also been shown to have hypoglycaemic effects in mice.

Lup-20(29)-en-28-olsure, 3-Hydroxy-, Methylester, (3β)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Lup-20(29)-en-28-olsure, 3-Hydroxy-, Methylester, (3β)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 63)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Mujin Biotechnology Co.,Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12825 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630
bess@weibangbio.com China 18145 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3619 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
sales@biopurify.com China 3772 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Aladdin Scientific

tp@aladdinsci.com United States 52924 58
Mensura Group Limited
+8618109034517
hkd008@vacorda.com China 2900 58
Meryer (Shanghai) Chemical Technology Co., Ltd. 021-61259108 18621169109
market03@meryer.com China 40228 62
BOC Sciences 1-631-485-4226; 16314854226
info@bocsci.com United States 14055 65
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548
cwb1@biopurify.cn China 2376 60

2259-06-5(Lup-20(29)-en-28-olsure, 3-Hydroxy-, Methylester, (3β)-)Verwandte Suche:


  • BETULINIC ACID METHYL ESTER
  • 3B-HYDROXY-LUP-20(29)-EN-28-OIC ACID METHYL ESTER
  • Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3beta)-
  • Methylbetulinate
  • BETULINIC ACID METHYL ESTER hplc
  • BETULINIC ACID METHYLESTER WITH HPLC
  • Lup-20(29)-en-28-oic acid, 3-hydroxy-, methyl ester, (3β)-
  • betulinate, Methyl
  • 2259-06-5
  • Tri-Terpenoids
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