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Mirogabalin besylate

Mirogabalin besylate Struktur
1138245-21-2
CAS-Nr.
1138245-21-2
Englisch Name:
Mirogabalin besylate
Synonyma:
Mirogabalin Besilate;Mirogabalin besylat;Mirogabalin besylate;Mirogabalin Besylate 10928;MIROGABALIN BENZENESULFONIC ACID;Mirogabalin besylate (DS 5565 besylate);2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid besylate;[(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0] hept-3-en-6-yl]acetic acid benzenesulfonate;((1R,5S,6S)-6-(carboxymethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)methanaminium benzenesulfonate;2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid compound with benzenesulfonic acid (1:1)
CBNumber:
CB73175483
Summenformel:
C18H25NO5S
Molgewicht:
367.46
MOL-Datei:
1138245-21-2.mol

Mirogabalin besylate Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMSO : 125 mg/mL (340.17 mM)
Aggregatzustand
Solid
Farbe
White to off-white
InChI
InChI=1/C12H19NO2.C6H6O3S/c1-2-8-3-9-5-12(7-13,6-11(14)15)10(9)4-8;7-10(8,9)6-4-2-1-3-5-6/h4,9-10H,2-3,5-7,13H2,1H3,(H,14,15);1-5H,(H,7,8,9)/t9-,10-,12-;/s3
InChIKey
OKJXJRVWXYRSAN-QWGAVYBYNA-N
SMILES
S(C1C=CC=CC=1)(O)(=O)=O.C([C@]1(C[C@@]2([H])CC(CC)=C[C@@]12[H])CN)C(=O)O |&1:11,13,20,r|

Sicherheit

Mirogabalin besylate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Mirogabalin besylate (mirogabalin, Tarlige) is a gabapentinoid therapy developed by Daiichi Sankyo, which is approved in Japan for the treatment of postherpetic neuralgia and painful diabetic peripheral neuropathy. Mirogabalin has a potent pain-modulating effect with a unique high affinity and prolonged dissociation rate for the a2delta-1 subunit of voltage-gated calcium (Ca2+) channels (VGCCs) on the dorsal root ganglion resulting in more sustained analgesia compared with traditional gabapentinoids[1].

Verwenden

Mirogabalin besylate is an oral gabapentin analogue for the treatment of peripheral neuralgia (PNP), including diabetic PNP and postherpetic neuralgia. The drug has been approved in Japan for the treatment of PNP and has not yet received FDA approval.

Mirogabalin besylate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Mirogabalin besylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • Mirogabalin besylate
  • Mirogabalin besylat
  • MIROGABALIN BENZENESULFONIC ACID
  • ((1R,5S,6S)-6-(carboxymethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)methanaminium benzenesulfonate
  • [(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0] hept-3-en-6-yl]acetic acid benzenesulfonate
  • 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid compound with benzenesulfonic acid (1:1)
  • Mirogabalin Besylate 10928
  • Mirogabalin besylate (DS 5565 besylate)
  • Mirogabalin Besilate
  • 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid besylate
  • 1138245-21-2
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