Amorfrutin B Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Amorfrutin B is a partial agonist of the peroxisome proliferator-activated receptor γ (PPARγ; K
i = 19 nM and EC
50 = 73 nM) that was first isolated from
A. fruticosa. It binds to PPARα and PPARβ/δ with K
i values of 2.6 and 1.7 μM, respectively. In insulin-resistant mice, 100 mg/kg/day amorfrutin B is reported to improve insulin sensitivity, glucose tolerance, and plasma lipid concentrations after two weeks of treatment.
Allgemeine Beschreibung
Natural product derived from plant source.
Amorfrutin B Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte