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GS 9451

GS 9451 Struktur
1098189-15-1
CAS-Nr.
1098189-15-1
Englisch Name:
GS 9451
Synonyma:
Vedroprevir;OTXAMWFYPMNDME-FQQWJMKMSA-N;Cyclopropanecarboxylic acid, N-[[(1α,3β,5α)-bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-, (1R,2R)-;Cyclopropanecarboxylic acid, N-[[(1α,3β,5α)-bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-, (1R,2R)-;(1R,2R)-N-[[(1alpha,3beta,5alpha)-Bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-cyclopropanecarboxylic acid
CBNumber:
CB73052043
Summenformel:
C45H60ClN7O9S
Molgewicht:
910.52
MOL-Datei:
1098189-15-1.mol

GS 9451 Eigenschaften

Dichte
1.38±0.1 g/cm3(Predicted)
pka
5.10±0.50(Predicted)

Sicherheit

GS 9451 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Vedroprevir is a pharmaceutical drug that is used in the treatment of hepatitis C virus in patients with HCV genotype 1 infection. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.

GS 9451 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Cyclopropanecarboxyl?ic acid, N-?[[(1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yloxy]?carbonyl]?-?3-?methyl-?L-?valyl-?(4R)?-?4-?[[8-?chloro-?2-?[2-?[(1-?methylethyl)?amino]?-?4-?thiazolyl]?-?7-?[2-?(4-?morpholinyl)?ethoxy]?-?4-?quinolinyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?- Cyclopropanecarboxyl?ic acid, N-?[[(1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yloxy]?carbonyl]?-?3-?methyl-?L-?valyl-?(4R)?-?4-?[[8-?chloro-?7-?(2,?2-?dimethoxyethoxy)?-?2-?[2-?[(1-?methylethyl)?amino]?-?4-?thiazolyl]?-?4-?quinolinyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?- Cyclopropanecarboxyl?ic acid, N-?[(1,?1-?dimethylethoxy)?carbonyl]?-?3-?methyl-?L-?valyl-?(4S)?-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?- 4-?Quinolinol, 8-?chloro-?7-?(2,?2-?dimethoxyethoxy)?-?2-?[2-?[(1-?methylethyl)?amino]?-?4-?thiazolyl]?- Ethanone, 1-?[2-?amino-?3-?chloro-?4-?(2,?2-?dimethoxyethoxy)?phenyl]?- Ethanone, 1-?(2-?amino-?3-?chloro-?4-?hydroxyphenyl)?- Carbonic acid, (1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yl (2,?5-?dioxo-?1-?pyrrolidinyl) ester L-?Proline, N-?[(1,?1-?dimethylethoxy)?carbonyl]?-?3-?methyl-?L-?valyl-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?, (4S)?- L-Proline, 4-[[(4-bromophenyl)sulfonyl]oxy]-, methyl ester, hydrochloride (1:1), (4S)- L-?Proline, N-?[(1,?1-?dimethylethoxy)?carbonyl]?-?3-?methyl-?L-?valyl-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?, methyl ester, (4S)?- CIS-BICYCLO[3.1.0]HEXAN-3-OL Cyclopropanecarboxyl?ic acid, N-?[[(1α,?3β,?5α)?-?bicyclo[3.1.0]?hex-?3-?yloxy]?carbonyl]?-?3-?methyl-?L-?valyl-?(4S)?-?4-?[[(4-?bromophenyl)?sulfonyl]?oxy]?-?L-?prolyl-?1-?amino-?2-?ethyl-?, methyl ester, (1R,?2R)?- Ethanone, 1-(2-amino-3-chloro-4-methoxyphenyl)-

Downstream Produkte

GS 9451 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 7)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Shanghai Han-Xiang Chemical Co., Ltd. 15971444841
 amber@biochempartner.com China 3061 58
Taizhou Crene Biotechnology Co. Ltd. +86-0576-88813233 +86-13396860566
 sales@pharm-intermediates.com China 1991 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44807 58
  • (1R,2R)-N-[[(1alpha,3beta,5alpha)-Bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-cyclopropanecarboxylic acid
  • Vedroprevir
  • OTXAMWFYPMNDME-FQQWJMKMSA-N
  • Cyclopropanecarboxylic acid, N-[[(1α,3β,5α)-bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-, (1R,2R)-
  • Cyclopropanecarboxylic acid, N-[[(1α,3β,5α)-bicyclo[3.1.0]hex-3-yloxy]carbonyl]-3-methyl-L-valyl-(4R)-4-[[8-chloro-2-[2-[(1-methylethyl)amino]-4-thiazolyl]-7-[2-(4-morpholinyl)ethoxy]-4-quinolinyl]oxy]-L-prolyl-1-amino-2-ethyl-, (1R,2R)-
  • 1098189-15-1
  • C45H60ClN7O9S
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