Carbamimidothioic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
2-[4-[(4-Nitrophenyl)methoxy]phenyl]ethyl Ester Carbamimidothioic Acid is an inhibitor of the reversed sodium-calcium exchanger (NCX). NCX is a potential therapeutic target for treatment in heart failure and myocardial ischemia-reperfusion.
Biochem/physiol Actions
KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation. NCX is the primary mechanism that prevents Ca2+ overload due to influx of calcium across the plasma membrane.
Carbamimidothioic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte